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IRAK1 抗体 (N-Term)

IRAK1 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3042847
发货至: 中国
  • 抗原 See all IRAK1 抗体
    IRAK1 (Interleukin-1 Receptor-Associated Kinase 1 (IRAK1))
    抗原表位
    • 31
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    AA 18-37, N-Term
    适用
    • 142
    • 86
    • 61
    • 2
    • 1
    • 1
    人, 大鼠
    宿主
    • 141
    • 13
    • 2
    克隆类型
    • 144
    • 12
    多克隆
    标记
    • 62
    • 8
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    This IRAK1 antibody is un-conjugated
    应用范围
    • 113
    • 69
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    Western Blotting (WB)
    原理
    Rabbit IgG polyclonal antibody for Interleukin-1 receptor-associated kinase 1(IRAK1) detection. Tested with WB in Human,Mouse,Rat.
    序列
    FLYEVPPWVM CRFYKVMDAL
    交叉反应 (详细)
    Predicted Cross Reactivity: mouse
    No cross reactivity with other proteins.
    Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.
    产品特性
    Rabbit IgG polyclonal antibody for Interleukin-1 receptor-associated kinase 1(IRAK1) detection. Tested with WB in Human,Mouse,Rat.
    Gene Name: interleukin-1 receptor-associated kinase 1
    Protein Name: Interleukin-1 receptor-associated kinase 1
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the N-terminus of human IRAK(18-37aa FLYEVPPWVMCRFYKVMDAL), identical to the related rat and mouse sequences.
    亚型
    IgG
    Top Product
    Discover our top product IRAK1 Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    储存液
    Thimerosal (Merthiolate), Sodium azide
    注意事项
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    有效期
    12 months
  • Liu, Wang, Qian, Li: "Xuebijing exerts protective effects on lung permeability leakage and lung injury by upregulating Toll-interacting protein expression in rats with sepsis." in: International journal of molecular medicine, Vol. 34, Issue 6, pp. 1492-504, (2014) (PubMed).

  • 抗原
    IRAK1 (Interleukin-1 Receptor-Associated Kinase 1 (IRAK1))
    别名
    IRAK1 (IRAK1 产品)
    别名
    IRAK1 antibody, IRAK antibody, pelle antibody, AA408924 antibody, IRAK-1 antibody, IRAK1-S antibody, Il1rak antibody, Plpk antibody, mPLK antibody, RGD1563841 antibody, interleukin 1 receptor associated kinase 1 antibody, interleukin-1 receptor-associated kinase 1 antibody, IRAK1 antibody, irak1 antibody, Irak1 antibody
    背景
    Interleukin-1 receptor-associated kinase 1, also called IRAK1, is an enzyme that in humans is encoded by the IRAK1 gene. By radiation hybrid analysis, this gene is mapped to chromosome Xq28. Serine/threonine-protein kinase plays a critical role in initiating innate immune response against foreign pathogens. This gene involved in Toll-like receptor(TLR) and IL-1R signaling pathways. This gene encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor(IL1R) upon stimulation. This gene is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B.

    Synonyms: Il1rak antibody|Interleukin 1 receptor associated kinase 1 antibody|Interleukin-1 receptor-associated kinase 1 antibody|IRAK antibody|IRAK-1 antibody|Irak1 antibody|IRAK1_HUMAN antibody|mPLK antibody|OTTHUMP00000026014 antibody|OTTHUMP00000026015 antibody|OTTHUMP00000026020 antibody|OTTHUMP00000180621 antibody|Pelle antibody|Pelle homolog antibody|Pelle-like protein kinase antibody|Plpk antibody
    UniProt
    P51617
    途径
    NF-kappaB Signaling, TLR signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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