IRAK1 抗体 (N-Term)
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北京 101111
Quick Overview for IRAK1 抗体 (N-Term) (ABIN3042847)
抗原
See all IRAK1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 18-37, N-Term
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原理
- Anti-IRAK/IRAK1 Antibody
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序列
- FLYEVPPWVM CRFYKVMDAL
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-IRAK/IRAK1 Antibody (ABIN3042847). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human IRAK, identical to the related rat and mouse sequences.
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亚型
- IgG
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anti-Interleukin-1 Receptor-Associated Kinase 1 (IRAK1) (AA 301-400) antibody
IRAK1 适用: 人, 大鼠 ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin-1 Receptor-Associated Kinase 1 (IRAK1) (AA 530-693) antibodyIRAK1 适用: 人 WB, ELISA, IF, IP, IHC (p) 宿主: 小鼠 Monoclonal 3F7 unconjugated
anti-Interleukin-1 Receptor-Associated Kinase 1 (IRAK1) (AA 530-693) antibodyIRAK1 适用: 人 WB, ELISA, IF, IP, IHC (p), RNAi 宿主: 小鼠 Monoclonal 3A9 unconjugated
anti-Interleukin-1 Receptor-Associated Kinase 1 (IRAK1) (AA 530-693) antibodyIRAK1 适用: 人 WB, IF, IP, IHC (p), EIA 宿主: 小鼠 Monoclonal 3A9 unconjugated
anti-Interleukin-1 Receptor-Associated Kinase 1 (IRAK1) (pThr209) antibodyIRAK1 适用: 人, 小鼠, 大鼠 WB, FACS, IF (cc), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin-1 Receptor-Associated Kinase 1 (IRAK1) (AA 424-633) antibodyIRAK1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Interleukin-1 Receptor-Associated Kinase 1 (IRAK1) (AA 348-381), (pSer376) antibodyIRAK1 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB56575 unconjugated
anti-Interleukin-1 Receptor-Associated Kinase 1 (IRAK1) (AA 683-712), (C-Term) antibodyIRAK1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB02337 unconjugated
anti-Interleukin-1 Receptor-Associated Kinase 1 (IRAK1) (AA 683-712) antibodyIRAK1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin-1 Receptor-Associated Kinase 1 (IRAK1) (pThr387) antibodyIRAK1 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Rat, Mouse
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说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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储存液
- Thimerosal (Merthiolate), Sodium azide
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注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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: "Xuebijing exerts protective effects on lung permeability leakage and lung injury by upregulating Toll-interacting protein expression in rats with sepsis." in: International journal of molecular medicine, Vol. 34, Issue 6, pp. 1492-504, (2014) (PubMed).
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: "Xuebijing exerts protective effects on lung permeability leakage and lung injury by upregulating Toll-interacting protein expression in rats with sepsis." in: International journal of molecular medicine, Vol. 34, Issue 6, pp. 1492-504, (2014) (PubMed).
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- IRAK1 (Interleukin-1 Receptor-Associated Kinase 1 (IRAK1))
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别名
- IRAK1
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背景
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Synonyms: Interleukin-1 receptor-associated kinase 1,IRAK-1,2.7.11.1,IRAK1,IRAK,
Tissue Specificity: Isoform 1 and isoform 2 are ubiquitously expressed in all tissues examined, with isoform 1 being more strongly expressed than isoform 2. .
Background: Interleukin-1 receptor-associated kinase 1, also called IRAK1, is an enzyme that in humans is encoded by the IRAK1 gene. By radiation hybrid analysis, this gene is mapped to chromosome Xq28. Serine/threonine-protein kinase plays a critical role in initiating innate immune response against foreign pathogens. This gene involved in Toll-like receptor (TLR) and IL-1R signaling pathways. This gene encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This gene is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B.
Sequence Similarities: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Pelle subfamily.
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分子量
- 274 kDa
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UniProt
- P51617
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途径
- NF-kappaB Signaling, TLR signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
抗原
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