FGFR4 抗体 (AA 22-206)
Quick Overview for FGFR4 抗体 (AA 22-206) (ABIN3042391)
抗原
See all FGFR4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 22-206
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原理
- Anti-FGFR4 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-FGFR4 Antibody Picoband® (ABIN3042391). Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human FGFR4 recombinant protein (Position: L22-H206). Human FGFR4 shares 86% and 84% amino acid (aa) sequences identity with mouse and rat FGFR4, respectively.
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亚型
- IgG
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anti-Fibroblast Growth Factor Receptor 4 (FGFR4) (AA 22-369) antibody
FGFR4 适用: 人, 猴 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 8A1G2 unconjugated
anti-Fibroblast Growth Factor Receptor 4 (FGFR4) (AA 22-369) antibodyFGFR4 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 3B5B8 unconjugated
anti-Fibroblast Growth Factor Receptor 4 (FGFR4) (AA 24-55), (N-Term) antibodyFGFR4 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB38171 unconjugated
anti-Fibroblast Growth Factor Receptor 4 (FGFR4) (AA 24-55) antibodyFGFR4 适用: 人 WB, ELISA, IHC, FACS, IF 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor 4 (FGFR4) (AA 31-145) antibodyFGFR4 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 1E2 unconjugated
anti-Fibroblast Growth Factor Receptor 4 (FGFR4) antibodyFGFR4 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Fibroblast Growth Factor Receptor 4 (FGFR4) antibodyFGFR4 适用: 人 ELISA, IHC 宿主: 小鼠 Monoclonal 4H2B10B2 unconjugated
anti-Fibroblast Growth Factor Receptor 4 (FGFR4) (AA 1-100) antibodyFGFR4 适用: 人, 大鼠 ELISA, IHC (p), IF (p), IF (cc), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor 4 (FGFR4) (AA 168-369) antibodyFGFR4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor 4 (FGFR4) (AA 25-182) antibodyFGFR4 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Western blot, 0.1-0.5 μg/mL, Human
1. Lesca, E., Lammens, A., Huber, R., Augustin, M. "Structural analysis of the human Fibroblast Growth Factor Receptor 4 kinase". J. Mol. Biol. 2. "Entrez Gene: FGFR4 fibroblast growth factor receptor 4" -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- FGFR4 (Fibroblast Growth Factor Receptor 4 (FGFR4))
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别名
- FGFR4
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背景
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Synonyms: Fibroblast growth factor receptor 4,FGFR-4,2.7.10.1,CD334,FGFR4,JTK2, TKF,
Tissue Specificity: Expressed in gastrointestinal epithelial cells, pancreas, and gastric and pancreatic cancer cell lines. .
Background: FGFR4 (Fibroblast growth factor receptor 4), also known as CD334, is a protein that in humans is encoded by the FGFR4 gene. It is mapped to 5q35.2. The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. It is overexpressed in gynecological tumor samples, suggesting a role in breast and ovarian tumorigenesis.
Sequence Similarities: Belongs to the protein kinase superfamily. Tyr protein kinase family. Fibroblast growth factor receptor subfamily.
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分子量
- 100 kDa
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基因ID
- 2264
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UniProt
- P22455
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding
抗原
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