The antibody 87G recognizes both membrane-bound and soluble forms of HLA-G (HLA-G1 and HLA-G5). HLA-G belongs to the MHC Class I molecules (MHC Class Ib, nonclassical) and it is expressed on the surface of trophoblast cells. The antibody 87G blocks interaction of HLA-G with inhibitory receptors.
纯化方法
Purified from hybridoma culture supernatant by protein-A affinity chromatography
免疫原
HLA-B27 transgenic mice were imunized with H-2 identical murine cells transfected with and expressing genes encoding HLA-G and Human beta2-microglobulin.
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
状态
Liquid
缓冲液
Azide free phosphate buffered saline (PBS), approx. pH 7.4, 0.2 μm filter sterilized. Endotoxin level is less than 0.01 EU/μg of the protein, as determined by the LAL test.
储存液
Azide free
储存条件
4 °C
储存方法
Store at 2-8°C. Do not freeze.
抗原
HLAG
(HLA Class I Histocompatibility Antigen, alpha Chain G (HLAG))