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Lamin A/C 抗体

This 小鼠 单克隆 antibody specifically detects Lamin A/C in WB, IHC, IF 和 IP. It exhibits reactivity toward 人 和 小鼠.It has been mentioned in 1 publication
产品编号 ABIN8071366
发货至: 中国
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Quick Overview for Lamin A/C 抗体 (ABIN8071366)

抗原

See all Lamin A/C (LMNA) 抗体
Lamin A/C (LMNA)

适用

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人, 小鼠

宿主

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小鼠

克隆类型

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单克隆

标记

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This Lamin A/C antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

克隆位点

JOL4
  • 原理

    Lamin A Monoclonal Antibody [JOL4] - Unpurified

    特异性

    The antibody reacts with both recombinant and native lamin A in humans, binding to an epitope between amino acids 572-646

    纯化方法

    Unpurified

    免疫原

    Recombinant human lamin A

    亚型

    IgG
  • 应用备注

    Optimal antibody dilution should be determined by titration, however as a guideline try, IP: Use neat.  WB: 1/50. Predicted molecular weight: 74 kDa. 

    说明

    Myeloma/fusion partners:Spleen cells from immunised BALB/c mice were fused with cells of the mouse SP2-0/Ag4 myeloma cell line

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Tissue culture supernatant containing 02M Tris/HCl pH 74 and 510

    储存条件

    4 °C
  • Vaughan, Alvarez-Reyes, Bridger, Broers, Ramaekers, Wehnert, Morris, Whitfield WGF, Hutchison: "Both emerin and lamin C depend on lamin A for localization at the nuclear envelope." in: Journal of cell science, Vol. 114, Issue Pt 14, pp. 2577-90, (2001) (PubMed).

  • 抗原

    Lamin A/C (LMNA)

    别名

    Lamin A

    背景

    70 kDa lamin antibody,CDCD1 antibody,CDDC antibody,CMD1A antibody,CMT2B1 antibody,EMD2antibody,FPL antibody,FPLD antibody,HGPS antibody,IDC antibody,LAMIN A antibody,lamin A/Cantibody,LAMIN C antibody,Lamin-A/C antibody,LDP1 antibody,LFP antibody,LGMD1B antibody,LMN 1antibody,LMN A antibody,LMN C antibody,LMN1 antibody,LMNA antibody,LMNA_HUMAN antibody,LMNC antibody,NYREN 32 antigen antibody,PRO1 antibody,Renal carcinoma antigen NY-REN-32 antibody

    OMIM

    150330

    途径

    Apoptosis, Caspase Cascade in Apoptosis, ER-Nucleus Signaling, Protein targeting to Nucleus
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