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Peroxiredoxin 5 抗体 (C-Term)

PRDX5 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3032191
发货至: 中国
  • 抗原 See all Peroxiredoxin 5 (PRDX5) 抗体
    Peroxiredoxin 5 (PRDX5)
    抗原表位
    • 8
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
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    C-Term
    适用
    • 44
    • 18
    • 15
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 50
    • 9
    • 2
    • 1
    克隆类型
    • 54
    • 7
    多克隆
    标记
    • 36
    • 11
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Peroxiredoxin 5 antibody is un-conjugated
    应用范围
    • 42
    • 24
    • 18
    • 13
    • 9
    • 7
    • 7
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    Antigen affinity
    免疫原
    An amino acid sequence from the C-terminus of human PRDX5 (DDSLVSIFGNRRLKRF) was used as the immunogen for this Peroxiredoxin 5 antibody (100% homologous in human, mouse and rat).
    亚型
    IgG
    Top Product
    Discover our top product PRDX5 Primary Antibody
  • 应用备注
    The stated application concentrations are suggested starting amounts. Titration of the Peroxiredoxin 5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    After reconstitution, the Peroxiredoxin 5 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    Peroxiredoxin 5 (PRDX5)
    Abstract
    PRDX5 产品
    别名
    acr1 antibody, aoeb166 antibody, pmp20 antibody, prx-5 antibody, prx5 antibody, prxv antibody, sbbi10 antibody, GB16965 antibody, zgc:112318 antibody, PRDX5 antibody, CG 32920 antibody, CG 7217 antibody, CG32920 antibody, CG7217 antibody, Dmel\\CG7217 antibody, dPrx5 antibody, dprx5 antibody, ACR1 antibody, AOEB166 antibody, B166 antibody, PLP antibody, PMP20 antibody, PRDX6 antibody, PRXV antibody, prx-V antibody, AOPP antibody, Pmp20 antibody, Prdx6 antibody, PrxV antibody, Aoeb166 antibody, Prx V antibody, peroxiredoxin 5 L homeolog antibody, peroxiredoxin-5, mitochondrial antibody, peroxiredoxin 5 antibody, Peroxiredoxin 5 antibody, prdx5.L antibody, LOC552429 antibody, prdx5 antibody, PRDX5 antibody, Prx5 antibody, Prdx5 antibody
    背景
    Peroxiredoxin 5, also known as PRX5 and PRDX5, is a member of the peroxiredoxin family and may play an antioxidant protective role in various tissues under nonpathologic conditions and during inflammatory processes. PRDX5 displays mitochondrial presequence features and has 3 cysteines implicated in antioxidant activity and a C-terminal SQL peroxisomal targeting sequence. Northern blot analysis revealed ubiquitous expression of a 1.0-kb PRDX5 transcript in tissues and cell lines. Functional analysis showed that Peroxiredoxin 5 has antioxidant activity equivalent to that of CAT. While PRDX5 was localized to fibroblasts in normal tendon, it was localized to fibroblasts and endothelial cells in degenerative tendon. mRNA and protein levels increased at 12 hours, and the increase in PRDX5 expression correlated with reduced peroxide levels. Peroxiredoxin 5 plays a protective role against oxidative stress in human cartilage.
    UniProt
    P30044
    途径
    Cell RedoxHomeostasis
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