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- 抗原 See all PAD4 (PADI4) 抗体
- PAD4 (PADI4) (Peptidyl Arginine Deiminase, Type IV (PADI4))
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抗原表位
- Middle Region
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PAD4 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- Antigen affinity
- 免疫原
- An amino acid sequence from the middle region of human PAD4 (ASPRSCYKLFQEQQNEGHGEA) was used as the immunogen for this PAD4 antibody.
- 亚型
- IgG
- Top Product
- Discover our top product PADI4 Primary Antibody
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anti-Peptidyl Arginine Deiminase, Type IV (PADI4) antibody
PADI4 适用: 人 WB, IHC, IF, IHC (p), FACS 宿主: 小鼠 Monoclonal 4H5 unconjugated
anti-Peptidyl Arginine Deiminase, Type IV (PADI4) (Center) antibodyPADI4 适用: 人, 小鼠 WB, IF, ICC, IHC (p), ChIP 宿主: 兔 Polyclonal unconjugated
anti-Peptidyl Arginine Deiminase, Type IV (PADI4) antibodyPADI4 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Peptidyl Arginine Deiminase, Type IV (PADI4) (N-Term) antibodyVerified PADI4 适用: 人 IHC, ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-Peptidyl Arginine Deiminase, Type IV (PADI4) (AA 374-550) antibodyPADI4 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Peptidyl Arginine Deiminase, Type IV (PADI4) (AA 299-588) antibodyPADI4 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 5E7 unconjugated
anti-Peptidyl Arginine Deiminase, Type IV (PADI4) (AA 1-300) antibodyPADI4 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Peptidyl Arginine Deiminase, Type IV (PADI4) antibodyPADI4 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Peptidyl Arginine Deiminase, Type IV (PADI4) (N-Term) antibodyPADI4 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Peptidyl Arginine Deiminase, Type IV (PADI4) (AA 299-588) antibodyPADI4 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 5B7 unconjugated
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- 应用备注
- The stated application concentrations are suggested starting amounts. Titration of the PAD4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
- 限制
- 仅限研究用
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- 缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- 储存条件
- -20 °C
- 储存方法
- After reconstitution, the PAD4 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- 抗原
- PAD4 (PADI4) (Peptidyl Arginine Deiminase, Type IV (PADI4))
- 别名
- PAD4 (PADI4 产品)
- 别名
- PAD antibody, PAD4 antibody, PADI5 antibody, PDI4 antibody, PDI5 antibody, Pad4 antibody, Pdi4 antibody, peptidyl arginine deiminase 4 antibody, peptidyl arginine deiminase, type IV antibody, PADI4 antibody, Padi4 antibody
- 背景
- Peptidylarginine Deiminase, Type IV is a human protein which in humans is encoded by the PADI4 gene. Peptidylarginine deiminases make up a family of posttranslational modification enzymes that convert arginine residues to citrulline residues in the presence of calcium ion(Nakashima et al., 1999). Suzuki et al.(2003) found from sequence data that the gene maps to 1p36. Cuthbert et al.(2004) described a process, deimination, that converts histone arginine to citrulline and antagonizes arginine methylation. They showed that the protein specifically deiminated arg2, arg8, arg17, and arg26 in the H3 tail. Deimination by PAD4 prevented arginine methylation by CARM1. Dimethylation of arginines prevented deimination by PAD4, although monomethylation still allowed deimination to take place. In vivo targeting experiments on an endogenous promoter demonstrated that the protein could repress hormone receptor-mediated gene induction. It was recruited to the pS2 promoter following hormone induction when the gene was transcriptionally downregulated, consistent with a repressive role.
- UniProt
- Q9UM07
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