电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

Oncostatin M 抗体 (Middle Region)

OSM 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3032094
发货至: 中国
  • 抗原 See all Oncostatin M (OSM) 抗体
    Oncostatin M (OSM)
    抗原表位
    • 15
    • 7
    • 6
    • 6
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 57
    • 10
    • 9
    宿主
    • 60
    • 7
    • 1
    • 1
    • 1
    克隆类型
    • 63
    • 7
    多克隆
    标记
    • 37
    • 8
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Oncostatin M antibody is un-conjugated
    应用范围
    • 56
    • 31
    • 13
    • 13
    • 9
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    Antigen affinity
    免疫原
    An amino acid sequence from the middle region of human Oncostatin M (ASDAFQRKLEGCRFLHGY) was used as the immunogen for this Oncostatin M antibody.
    亚型
    IgG
    Top Product
    Discover our top product OSM Primary Antibody
  • 应用备注
    The stated application concentrations are suggested starting amounts. Titration of the Oncostatin M antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    After reconstitution, the Oncostatin M antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    Oncostatin M (OSM)
    别名
    Oncostatin M (OSM 产品)
    别名
    OSM antibody, OncoM antibody, oncostatin M antibody, OSM antibody, Osm antibody
    背景
    Oncostatin M (OSM) is a member of a cytokine family that includes leukemia-inhibitory factor, granulocyte colony-stimulating factor, and interleukin 6. This gene encodes a growth regulator which inhibits the proliferation of a number of tumor cell lines. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. OSM has the ability to inhibit the growth of human A375 melanoma cells but not normal human fibroblasts. Treatment with recombinant OSM leads to the inhibition of proliferation and changes in cellular morphology of a number of tumor cell lines derived from a wide variety of tissue types. OSM also has the ability to inhibit the proliferation of murine M1 myeloid leukemic cells and can induce their differentiation into macrophage-like cells, a function shared by LIF, CSF3, and IL6.
    UniProt
    P13725
    途径
    JAK/STAT Signaling, Negative Regulation of Hormone Secretion
You are here:
客服