-
- 抗原 See all NOL3 抗体
- NOL3 (Nucleolar Protein 3 (Apoptosis Repressor with CARD Domain) (NOL3))
-
抗原表位
- AA 91-106
-
适用
- 人, 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This NOL3 antibody is un-conjugated
-
应用范围
- Western Blotting (WB)
- 纯化方法
- Antigen affinity
- 免疫原
- Amino acids 91-106 (WDWQHVGPGYRDRSYD-human) were used as the immunogen for this ARC antibody (100% rat homology).
- 亚型
- IgG
- Top Product
- Discover our top product NOL3 Primary Antibody
-
anti-Nucleolar Protein 3 (Apoptosis Repressor with CARD Domain) (NOL3) antibody
NOL3 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Nucleolar Protein 3 (Apoptosis Repressor with CARD Domain) (NOL3) (C-Term) antibodyNOL3 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nucleolar Protein 3 (Apoptosis Repressor with CARD Domain) (NOL3) (AA 1-197) antibodyNOL3 适用: 人, 小鼠 WB, IHC, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Nucleolar Protein 3 (Apoptosis Repressor with CARD Domain) (NOL3) (AA 1-208) antibodyNOL3 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Nucleolar Protein 3 (Apoptosis Repressor with CARD Domain) (NOL3) (AA 191-208) antibodyNOL3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Nucleolar Protein 3 (Apoptosis Repressor with CARD Domain) (NOL3) (AA 1-208) antibodyNOL3 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Nucleolar Protein 3 (Apoptosis Repressor with CARD Domain) (NOL3) (AA 1-208) antibodyNOL3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6F5 unconjugated
anti-Nucleolar Protein 3 (Apoptosis Repressor with CARD Domain) (NOL3) (AA 191-208) antibodyNOL3 适用: 人, 小鼠 WB, IHC, IHC (p), IP 宿主: 兔 Polyclonal unconjugated
anti-Nucleolar Protein 3 (Apoptosis Repressor with CARD Domain) (NOL3) antibodyNOL3 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Nucleolar Protein 3 (Apoptosis Repressor with CARD Domain) (NOL3) (AA 159-208) antibodyNOL3 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
- The stated application concentrations are suggested starting amounts. Titration of the ARC antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
- 限制
- 仅限研究用
-
- 缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- 储存条件
- -20 °C
- 储存方法
- After reconstitution, the ARC antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
-
- 抗原
- NOL3 (Nucleolar Protein 3 (Apoptosis Repressor with CARD Domain) (NOL3))
- 别名
- ARC Apoptosis Repressor with CARD (NOL3 产品)
- 别名
- ARC antibody, FCM antibody, MYP antibody, NOP antibody, NOP30 antibody, B430311C09Rik antibody, MYC antibody, Nop30 antibody, Arc antibody, nucleolar protein 3 antibody, nucleolar protein 3 (apoptosis repressor with CARD domain) antibody, NOL3 antibody, Nol3 antibody
- 背景
- Apoptosis Repressor with CARD, also known as ARC, NOP30, NOL3, CARD2 and MYP, is a protein that in humans is encoded by the NOL3 gene. NOL3 has been shown to interact with SFRS9 and Caspase 8. By genomic sequence analysis, Stoss et al.(1999) determined that the NOL3 gene, which encodes NOP30 and MYP and which they called NOP, is composed of 4 exons. The alternative 5-prime splice site that generates the two isoforms is located in exon 2. It is reported that expression of the Apoptosis Repressor with CARD/ARC cDNA encoding the smaller transcript inhibited apoptosis in a dose-dependent manner when coexpressed with CASP8 but not when coexpressed with CASP9. The protein also inhibited apoptosis induced by stimulation of CD95/FAS, tumor necrosis factor receptor-1, and TRAMP/death receptor-3. Enzymatic analysis showed that ARC inhibits the enzymatic activity of CASP8. Immunoprecipitation and immunoblot analysis indicated that ARC interacts with CASP2 and -8 through its N-terminal death effector domain but does not interact with CASP1, -3, or -9.
- UniProt
- O60936
-
You are here:
