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Neuregulin 2 抗体 (Middle Region)

This anti-Neuregulin 2 antibody is a 兔 多克隆 antibody detecting Neuregulin 2 in WB. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN3031975
发货至: 中国

Quick Overview for Neuregulin 2 抗体 (Middle Region) (ABIN3031975)

抗原

See all Neuregulin 2 (NRG2) 抗体
Neuregulin 2 (NRG2)

适用

  • 33
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  • 5
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  • 1
人, 大鼠, 小鼠

宿主

  • 34
  • 4

克隆类型

  • 35
  • 3
多克隆

标记

  • 20
  • 5
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Neuregulin 2 antibody is un-conjugated

应用范围

  • 20
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  • 17
  • 6
  • 5
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  • 3
  • 2
Western Blotting (WB)
  • 抗原表位

    • 8
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    纯化方法

    Antigen affinity

    免疫原

    An amino acid sequence from the middle region of human NRG2 (NGRKNSRLQFNKVKVEDA) was used as the immunogen for this NRG2 antibody.

    亚型

    IgG
  • 应用备注

    The stated application concentrations are suggested starting amounts. Titration of the NRG2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

    限制

    仅限研究用
  • 缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    -20 °C

    储存方法

    After reconstitution, the NRG2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原

    Neuregulin 2 (NRG2)

    别名

    NRG2

    背景

    Neuregulin 2, also known as DON1 or NTAK, is a protein that in humans is encoded by the NRG2 gene. Neuregulin 2 is a member of the neuregulin family of growth and differentiation factors. Through interaction with the ErbB family of receptors, NRG2 induces the growth and differentiation of epithelial, neuronal, glial, and other types of cells. The human gene contains 12 exons and the mouse Nrg2 gene contains 12 exons and spans about 180 kb. The genomic structure is similar to that of neuregulin 1(NRG1), another member of the neuregulin family of ligands. NRG1 and NRG2 mediate distinct biological processes by acting at different sites in tissues and eliciting different biological responses in cells. In particular, the neuregulin-ERBB signaling pathways play crucial roles in regulating the proliferation and differentiation of Schwann cells, the myelin-forming cells in the peripheral nervous system.

    UniProt

    O14511

    途径

    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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