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- 抗原 See all MRP1 抗体
- MRP1 (Macrophage Inflammatory Protein Related Protein 1 (MRP1))
- 适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MRP1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- Antigen affinity
- 免疫原
- Amino acids LLQQRGLFYSMAKDAGLV (human) were used as the immunogen for this MRP1 antibody.
- 亚型
- IgG
- Top Product
- Discover our top product MRP1 Primary Antibody
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anti-Macrophage Inflammatory Protein Related Protein 1 (MRP1) (AA 501-600) antibody
MRP1 适用: 人, 大鼠 WB, FACS, IF (cc), IF (p), ELISA, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Macrophage Inflammatory Protein Related Protein 1 (MRP1) antibodyMRP1 适用: 人, 小鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- The stated application concentrations are suggested starting amounts. Titration of the MRP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
- 限制
- 仅限研究用
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- 缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- 储存条件
- -20 °C
- 储存方法
- After reconstitution, the MRP1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- 抗原
- MRP1 (Macrophage Inflammatory Protein Related Protein 1 (MRP1))
- 别名
- MRP1 (MRP1 产品)
- 别名
- Abcc1a antibody, Avcc1a antibody, Mrp antibody, Mrp1 antibody, BTCC-1 antibody, DRAP-27 antibody, MIC3 antibody, MRP-1 antibody, TSPAN-29 antibody, TSPAN29 antibody, Scya6 antibody, c10 antibody, ATP binding cassette subfamily C member 1 antibody, CD9 molecule antibody, chemokine (C-C motif) ligand 6 antibody, Abcc1 antibody, CD9 antibody, Ccl6 antibody
- 背景
- ABCC1 (ATP-binding cassette, subfamily C, member 1), also called MRP1, is a protein that in humans is encoded by the ABCC1 gene. ABCC1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. It is a plasma membrane drug-efflux pump.The gene is mapped to chromosome 16p13.1 by isotopic in situ hybridization. ABCC1/MRP1 functions as a multispecific organic anion transporter, with oxidized glutathione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates and it also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Blocking MRP1 efflux pumps increases the susceptibility of the cells to the toxic effects of unconjugated bilirubin, suggesting that it is an important protector in this scenario. The protein clears beta-amyloid from brains of mice and can be activated by thiethylperazine. And Chemotaxis assays show that MPR1-mediated transport of S1P influenced mast-cell migration, but not mast-cell degranulation.
- UniProt
- P33527
- 途径
- Response to Water Deprivation, Cell-Cell Junction Organization
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