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HSD17B6 抗体 (C-Term)

HSD17B6 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3031275
发货至: 中国
  • 抗原 See all HSD17B6 抗体
    HSD17B6 (Hydroxysteroid (17-Beta) Dehydrogenase 6 (HSD17B6))
    抗原表位
    • 16
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    C-Term
    适用
    • 34
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    宿主
    • 32
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    克隆类型
    • 34
    多克隆
    标记
    • 12
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    This HSD17B6 antibody is un-conjugated
    应用范围
    • 27
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    • 13
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    Antigen affinity
    免疫原
    An amino acid sequence from the C-terminus of human HSD17B6 (SLADYILTRSWPKPAQAV) was used as the immunogen for this HSD17B6 antibody.
    亚型
    IgG
    Top Product
    Discover our top product HSD17B6 Primary Antibody
  • 应用备注
    The stated application concentrations are suggested starting amounts. Titration of the HSD17B6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    Store the HSD17B6 antibody at -20°C.
  • 抗原
    HSD17B6 (Hydroxysteroid (17-Beta) Dehydrogenase 6 (HSD17B6))
    别名
    HSD17B6 (HSD17B6 产品)
    别名
    HSE antibody, RODH antibody, SDR9C6 antibody, 17betaHSD9 antibody, Hsd17b9 antibody, Rdh8 antibody, hydroxysteroid 17-beta dehydrogenase 6 antibody, hydroxysteroid (17-beta) dehydrogenase 6 antibody, HSD17B6 antibody, Hsd17b6 antibody
    背景
    Hydroxysteroid 17-beta dehydrogenase 6 is an enzyme that in humans is encoded by the HSD17B6 gene. The protein encoded by this gene has both oxidoreductase and epimerase activities and is involved in androgen catabolism. Baker ME et al point out expression of 17beta-HSDs had an important role in the early evolution of the physiological response to androgens and estrogens. Biswas and Russell concluded that 17beta-HSD6 and RoDH play opposing roles in androgen action, 17beta-HSD6 inactivates 3alpha-adiol by conversion to androsterone and RoDH activates 3alpha-adiol by conversion to dihydrotestosterone. The synthesis of an active steroid hormone by back conversion of an inactive metabolite represents a potentially important mechanism by which the steady state level of a transcriptional effector can be regulated.
    UniProt
    O14756
    途径
    Steroid Hormone Biosynthesis
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