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GAD 抗体 (AA 14-122)

GAD1 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3031060
发货至: 中国
  • 抗原 See all GAD (GAD1) 抗体
    GAD (GAD1) (Glutamate Decarboxylase 1 (Brain, 67kDa) (GAD1))
    抗原表位
    • 15
    • 13
    • 11
    • 8
    • 7
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 14-122
    适用
    • 90
    • 54
    • 50
    • 6
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 大鼠
    宿主
    • 81
    • 15
    • 2
    • 2
    克隆类型
    • 77
    • 23
    多克隆
    标记
    • 54
    • 11
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GAD antibody is un-conjugated
    应用范围
    • 80
    • 32
    • 31
    • 13
    • 13
    • 12
    • 12
    • 10
    • 9
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    Antigen affinity
    免疫原
    Human partial recombinant protein (AA 14-122) was used as the immunogen for this GAD67 antibody.
    亚型
    IgG
    Top Product
    Discover our top product GAD1 Primary Antibody
  • 应用备注
    The stated application concentrations are suggested starting amounts. Titration of the GAD67 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    After reconstitution, the GAD67 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    GAD (GAD1) (Glutamate Decarboxylase 1 (Brain, 67kDa) (GAD1))
    别名
    GAD67 (GAD1 产品)
    别名
    CPSQ1 antibody, GAD antibody, SCP antibody, GAD-67 antibody, cpsq1 antibody, gad1 antibody, gad1-A antibody, gad67 antibody, GAD67 antibody, GAD1 antibody, GLUTAMATE DECARBOXYLASE antibody, GLUTAMATE DECARBOXYLASE 1 antibody, MKP11.30 antibody, MKP11_30 antibody, glutamate decarboxylase antibody, EP10 antibody, GAD25 antibody, GAD44 antibody, Gad-1 antibody, Gad67 antibody, glutamate decarboxylase 1 antibody, glutamate decarboxylase 1 L homeolog antibody, glutamate decarboxylase antibody, glutamate decarboxylase 1b antibody, GAD1 antibody, gad1.1.L antibody, GAD antibody, Gad1 antibody, gad1b antibody
    背景
    Glutamate decarboxylase 1 (GAD67), also known as GAD1, is a human gene. This gene encodes one of several forms of glutamic acid decarboxylase identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this GAD67 has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. It may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form.
    基因ID
    2571
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