电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

FAS 抗体 (N-Term)

This anti-FAS antibody is a 兔 多克隆 antibody detecting FAS in WB, IHC (fro) 和 IHC (p). Suitable for 大鼠 和 小鼠.
产品编号 ABIN3030901
发货至: 中国

Quick Overview for FAS 抗体 (N-Term) (ABIN3030901)

抗原

See all FAS 抗体
FAS (TNF Receptor Superfamily, Member 6 (FAS))

适用

  • 249
  • 71
  • 64
  • 19
  • 6
  • 5
  • 5
  • 4
  • 2
  • 1
  • 1
大鼠, 小鼠

宿主

  • 184
  • 120
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1

克隆类型

  • 180
  • 130
  • 1
多克隆

标记

  • 146
  • 30
  • 28
  • 13
  • 12
  • 7
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This FAS antibody is un-conjugated

应用范围

  • 188
  • 124
  • 106
  • 76
  • 59
  • 39
  • 32
  • 31
  • 26
  • 26
  • 21
  • 18
  • 14
  • 8
  • 5
  • 5
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 24
    • 23
    • 16
    • 16
    • 8
    • 8
    • 7
    • 6
    • 6
    • 6
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    纯化方法

    Antigen affinity

    免疫原

    An amino acid sequence from the N-terminus of rat CD95 (YTDRKHYSDKCRRCAFCDEGHGL) was used as the immunogen for this CD95 antibody.

    亚型

    IgG
  • 应用备注

    The stated application concentrations are suggested starting amounts. Titration of the CD95 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,IHC (Frozen): 0.5-1 μg/mL

    限制

    仅限研究用
  • 缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    -20 °C

    储存方法

    After reconstitution, the CD95 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原

    FAS (TNF Receptor Superfamily, Member 6 (FAS))

    别名

    CD95

    背景

    FAS(also known as surface antigen APO1 or CD95) is a member of the tumour-necrosis receptor factor family of death receptors, can induce apoptosis or, conversely, can deliver growth stimulatory signals. It acts as an inducer of both neurite growth in vitro and accelerated recovery after nerve injury in vivo. Fas antigen is expressed and functional on papillary thyroid cancer cells and this may have potential therapeutic significance. The FAS antigen shows structural homology with a number of cell surface receptors, including tumor necrosis factor(TNF) receptors and the low-affinity nerve growth factor receptor(NGFR) and is mapped to 10q24.1. And the FAS and FASL system plays a key role in regulating apoptotic cell death and corruption of this signalling pathway has been shown to participate in immune escape and tumorigenesis.

    UniProt

    Q63199

    途径

    p53 Pathway, Apoptosis, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
You are here:
Chat with us!