CAMKK2 抗体 (Middle Region)
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- 抗原 See all CAMKK2 抗体
- CAMKK2 (Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2))
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抗原表位
- Middle Region
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CAMKK2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
- 纯化方法
- Antigen affinity
- 免疫原
- An amino acid sequence from the middle region of CaMKK2 (KLAYNENDNTYYAMK) was used as the immunogen for this CaMKK2 antibody (100% homologous in human, mouse and rat).
- 亚型
- IgG
- Top Product
- Discover our top product CAMKK2 Primary Antibody
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anti-Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2) (AA 1-130) antibody
CAMKK2 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 1A11 unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2) (AA 1-541) antibodyCAMKK2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2) (AA 2-137) antibodyCAMKK2 适用: 人 WB, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2) (C-Term) antibodyCAMKK2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2) (N-Term) antibodyKO Validated CAMKK2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2) (AA 483-512), (C-Term) antibodyCAMKK2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB12560 unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2) (N-Term) antibodyCAMKK2 适用: 人, 小鼠, 大鼠, Pig, 豚鼠, 兔, Cow, 犬, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2) (AA 43-71), (N-Term) antibodyCAMKK2 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2) antibodyCAMKK2 适用: 人, 小鼠 WB, ELISA 宿主: 小鼠 Monoclonal 239CT7-5-3 unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2) (AA 483-512) antibodyCAMKK2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- The stated application concentrations are suggested starting amounts. Titration of the CaMKK2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,Immunocytochemistry: 0.5-1 μg/mL
- 限制
- 仅限研究用
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- 缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- 储存条件
- -20 °C
- 储存方法
- After reconstitution, the CaMKK2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- 抗原
- CAMKK2 (Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2))
- 别名
- CaMKK2 (CAMKK2 产品)
- 别名
- CAMKK antibody, CAMKKB antibody, 6330570N16Rik antibody, AW061083 antibody, mKIAA0787 antibody, camk2b antibody, fj90d04 antibody, wu:fj90d04 antibody, si:dkey-174n20.2 antibody, CAMKK2 antibody, calcium/calmodulin dependent protein kinase kinase 2 antibody, calcium/calmodulin-dependent protein kinase kinase 2, beta antibody, calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 1 antibody, calcium/calmodulin dependent protein kinase II beta antibody, calcium/calmodulin-dependent protein kinase kinase 2 antibody, CAMKK2 antibody, Camkk2 antibody, camk2b1 antibody, CAMK2B antibody, camkk2 antibody
- 背景
- Calcium/calmodulin-dependent protein kinase kinase 2, is an enzyme that in humans is encoded by the CaMKK2 gene. The product of this gene belongs to the serine/threonine-specific protein kinase family, and to the Ca++/calmodulin-dependent protein kinase subfamily. This protein plays a role in the calcium/calmodulin-dependent(CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4. CaMKK2 regulates production of the appetite stimulating hormone neuropeptide Y and functions as an AMPK kinase in the hypothalamus. It also has an important role in the development of hyperalgesia and tolerance to opioid analgesic drugs, through reduction in downstream signalling pathways and mu opioid receptor downregulation. Inhibition of CaMKK2 in mice reduces appetite and promotes weight loss.
- UniProt
- Q96RR4
- 途径
- AMPK Signaling
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