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BMPR1B 抗体 (Middle Region)

BMPR1B 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3030189
发货至: 中国
  • 抗原 See all BMPR1B 抗体
    BMPR1B (Bone Morphogenetic Protein Receptor, Type IB (BMPR1B))
    抗原表位
    • 12
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    Middle Region
    适用
    • 113
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    • 4
    • 4
    • 1
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    人, 小鼠, 大鼠
    宿主
    • 102
    • 11
    克隆类型
    • 104
    • 9
    多克隆
    标记
    • 45
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    This BMPR1B antibody is un-conjugated
    应用范围
    • 99
    • 71
    • 32
    • 6
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
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    Western Blotting (WB)
    纯化方法
    Antigen affinity
    免疫原
    An amino acid sequence from the middle region of human Bone Morphogenetic Protein Receptor Type IB (FCYFRYKRQETRPRYS) was used as the immunogen for this BMPR1B antibody.
    亚型
    IgG
    Top Product
    Discover our top product BMPR1B Primary Antibody
  • 应用备注
    The stated application concentrations are suggested starting amounts. Titration of the BMPR1B antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    After reconstitution, the BMPR1B antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    BMPR1B (Bone Morphogenetic Protein Receptor, Type IB (BMPR1B))
    别名
    BMPR1B (BMPR1B 产品)
    别名
    ALK6 antibody, BMPR-IB antibody, FecB antibody, alk-6 antibody, alk6 antibody, cdw293 antibody, alk6b antibody, zgc:172219 antibody, BMPR1B antibody, AI385617 antibody, ALK-6 antibody, AV355320 antibody, Acvrlk6 antibody, Alk6 antibody, BMPR-1B antibody, CFK-43a antibody, SKR6 antibody, BR1b antibody, alk6tr antibody, bmpr1b antibody, zALK-6 antibody, zgc:92220 antibody, CDw293 antibody, BMP15 antibody, BMPRIB antibody, RPK-1 antibody, bone morphogenetic protein receptor type 1B antibody, bone morphogenetic protein receptor, type IBb antibody, bone morphogenetic protein receptor, type 1B antibody, bone morphogenetic protein receptor, type IBa antibody, BMPR1B antibody, bmpr1b antibody, bmpr1bb antibody, Bmpr1b antibody, bmpr1ba antibody
    背景
    Bone Morphogenetic Protein Receptor Type IB, also known as ALK6, is a protein which in humans is encoded by the BMPR1B gene. It is a member of the bone morphogenetic protein(BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine(threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. By analysis of a monochromosome hybrid mapping panel and by FISH, Astrom et al.(1999) mapped the BMPR1B gene to chromosome 4q22-q24. Ide et al.(1997) compared BMP receptor expression in normal and cancerous prostate tissues. While BMPR1A and BMPR2 were expressed at similar levels in all prostate tissues, BMPR1B was expressed at a significantly reduced level in cancerous prostate tissue.
    UniProt
    O00238
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