The stated application concentrations are suggested starting amounts. Titration of the ABCG4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
限制
仅限研究用
缓冲液
0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
储存条件
-20 °C
储存方法
After reconstitution, the ABCG4 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
抗原
ABCG4
(ATP-Binding Cassette, Sub-Family G (WHITE), Member 4 (ABCG4))
WHITE2 antibody, 6430517O04Rik antibody, zgc:171697 antibody, ATP binding cassette subfamily G member 4 antibody, ATP-binding cassette sub-family G member 4 antibody, ATP-binding cassette, sub-family G (WHITE), member 4a antibody, ATP-binding cassette, sub-family G (WHITE), member 4b antibody, ABCG4 antibody, CpipJ_CPIJ007191 antibody, CpipJ_CPIJ012365 antibody, CpipJ_CPIJ012372 antibody, CpipJ_CPIJ014443 antibody, CpipJ_CPIJ019125 antibody, CpipJ_CPIJ020198 antibody, PAAG_06842 antibody, Abcg4 antibody, LOC550918 antibody, abcg4a antibody, abcg4b antibody
背景
ATP-Binding Cassette, Subfamily G, Member 4 is a protein that in humans is encoded by the ABCG4 gene. The protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. This protein is a member of the White subfamily and is expressed predominantly in liver tissue. By genomic sequence analysis, Engel et al.(2001) mapped the gene to chromosome 11q23.3. Engel et al.(2001) demonstrated 5-fold induction of ABCG4 following treatment of normal monocyte-derived macrophages with the LXR and RXR agonists 9-cis retinoic acid and 22R hydroxycholesterol. Removal of cholesterol from macrophages by cyclodextrin decreased ABCG4 message levels.