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ABCG1 抗体 (C-Term)

ABCG1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3030057
发货至: 中国
  • 抗原 See all ABCG1 抗体
    ABCG1 (ATP-Binding Cassette, Sub-Family G (WHITE), Member 1 (ABCG1))
    抗原表位
    • 16
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 58
    • 29
    • 27
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 55
    • 3
    • 1
    克隆类型
    • 45
    • 14
    多克隆
    标记
    • 25
    • 7
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ABCG1 antibody is un-conjugated
    应用范围
    • 43
    • 18
    • 16
    • 15
    • 14
    • 13
    • 8
    • 7
    • 3
    • 3
    • 3
    • 2
    Western Blotting (WB)
    纯化方法
    Antigen affinity
    免疫原
    An amino acid sequence from the C-terminus of human ABCG1 (ETCHFQKSEAILRELDVENAK) was used as the immunogen for this ABCG1 antibody (100% homologous in human, mouse and rat).
    亚型
    IgG
    Top Product
    Discover our top product ABCG1 Primary Antibody
  • 应用备注
    The stated application concentrations are suggested starting amounts. Titration of the ABCG1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    After reconstitution, the ABCG1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    ABCG1 (ATP-Binding Cassette, Sub-Family G (WHITE), Member 1 (ABCG1))
    别名
    ABCG1 (ABCG1 产品)
    别名
    ABCG1 antibody, zgc:162197 antibody, ABC8 antibody, WHITE1 antibody, AW413978 antibody, Abc8 antibody, White antibody, ATP binding cassette subfamily G member 1 antibody, ATP-binding cassette, sub-family G (WHITE), member 1 antibody, ABCG1 antibody, abcg1 antibody, Abcg1 antibody
    背景
    ABCG1 (ATP-binding cassette, subfamily G, member 1) also known as ABC8, is a protein that in humans is encoded by the ABCG1 gene. ABCG1 is a regulator of macrophage cholesterol and phospholipid transport. The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. The gene is mapped on 21q22.3. This protein is a member of the White subfamily. It is involved in macrophage cholesterol and phospholipids transport, and may regulate cellular lipid homeostasis in other cell types. ABCG1 is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. Inhibition of ABCG1 protein expression using an antisense strategy resulted in reduced HDL3-dependent efflux of cholesterol and choline-phospholipids. In macrophages, silencing of GPS2 by RNA interference reducedABCG1expression and diminished ABCG1-mediated cholesterol efflux.
    UniProt
    P45844
    途径
    Lipid Metabolism
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