NF-kB p65 抗体 (Middle Region)
Our Local Distributor
北京 101111
Quick Overview for NF-kB p65 抗体 (Middle Region) (ABIN3029746)
抗原
See all NF-kB p65 (NFkBP65) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- Middle Region
-
纯化方法
- Antigen affinity
-
免疫原
- An amino acid sequence from the middle region of the human protein (VPIEEQRGDYDLNAVR) was used as the immunogen for this p65 antibody (100% homologous in human, mouse and rat).
-
亚型
- Ig Fraction
-
-
anti-Nuclear Factor-kB p65 (NFkBP65) (AA 51-100) antibody
NFkBP65 适用: 人, 小鼠, 大鼠, Cow, 斑马鱼, 兔, 小鸡 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Factor-kB p65 (NFkBP65) (pSer536) antibodyNFkBP65 适用: 人, 小鼠, 大鼠, Cow, 小鸡 WB, ELISA, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Factor-kB p65 (NFkBP65) (pSer536) antibodyNFkBP65 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IP, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Factor-kB p65 (NFkBP65) antibodyNFkBP65 适用: 人, 小鼠, 大鼠, 斑马鱼 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Factor-kB p65 (NFkBP65) (Center) antibodyNFkBP65 适用: 人, 小鼠 WB, IF, IHC (p), ICC, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Factor-kB p65 (NFkBP65) (AA 19-306) antibodyNFkBP65 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Factor-kB p65 (NFkBP65) (AA 50-180) antibodyNFkBP65 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Factor-kB p65 (NFkBP65) (pThr435) antibodyNFkBP65 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IP, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Factor-kB p65 (NFkBP65) (pSer281) antibodyNFkBP65 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Factor-kB p65 (NFkBP65) antibodyKD Validated NFkBP65 适用: 人 WB, FACS, ICC, IF (p) 宿主: 兔 Monoclonal 23GB1490 unconjugated Recombinant Antibody
-
-
应用备注
- The stated application concentrations are suggested starting points. Titration of the p65 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,Immunocytochemistry: 0.5-1 μg/mL
-
限制
- 仅限研究用
-
-
-
缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
-
储存条件
- -20 °C
-
储存方法
- After reconstitution, the p65 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
-
-
- NF-kB p65 (NFkBP65) (Nuclear Factor-kB p65 (NFkBP65))
-
别名
- p65 NF-kB
-
背景
- RELA, also called NFKB3 or NFKB, p65 subunit is part of the NF-kB complex. The complex is inhibited by I-kappa-B proteins, which inactivates NFkB by trapping it in the cytoplasm. The p65 heterodimer is the most abundant form of NF-kB. It is a nonhistone substrate of HDAC3 and that IKBA-dependent nuclear export of the HDAC3-deacetylated RELA replenishes the depleted cytoplasmic pool of latent NFKB-IKBA complexes for subsequent NF-kB responses. Its nucleocytoplasmic redistribution coincided with export of PPARG, and immunoprecipitation analysis indicated that PPARG-RELA association was dependent on the PPARG C-terminal ligand-binding domain. IKK-dependent phosphorylation of RELA on Ser468 enhanced binding of GCN5 to RELA and its ubiquitination.
-
UniProt
- Q04206
-
途径
- NF-kappaB Signaling, RTK signaling, TCR Signaling, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Toll-Like Receptors Cascades, S100 Proteins
抗原
-
