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Caspase 1 抗体 (Large Subunit, N-Term)

This anti-Caspase 1 antibody is a 兔 多克隆 antibody detecting Caspase 1 in WB 和 IHC (p). Suitable for 人.
产品编号 ABIN3028535
发货至: 中国
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Quick Overview for Caspase 1 抗体 (Large Subunit, N-Term) (ABIN3028535)

抗原

See all Caspase 1 (CASP1) 抗体
Caspase 1 (CASP1)

适用

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宿主

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克隆类型

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  • 43
多克隆

标记

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This Caspase 1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    Large Subunit, N-Term

    纯化方法

    Antigen affinity

    免疫原

    An amino acid sequence from the N-terminus of human CASP1 (CSLEEAQRIWKQKSAEIY) was used as the immunogen for this Caspase-1 antibody. The sequence is from the large subunit.

    亚型

    IgG
  • 应用备注

    Titration of the Caspase-1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

    限制

    仅限研究用
  • 缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    -20 °C

    储存方法

    The lyophilized Caspase-1 antibody can be stored at 4°C. After reconstitution, aliquot and store at -20°C. Repeated freeze/thaw steps should be avoided.
  • 抗原

    Caspase 1 (CASP1)

    别名

    Caspase-1

    背景

    Caspase-1 is a cysteine protease that regulates inflammatory processes through its capacity to process and activate the interleukin-1-beta, interleukin 18, and interleukin 33 precursor proteins. The Caspase-1 gene consists of 10 exons spanning at least 10.6 kb and is mapped to 11q23, a site frequently involved in rearrangement in human cancers, including a number of leukemias and lymphomas.

    UniProt

    P29466

    途径

    Apoptosis, Interferon-gamma Pathway, Positive Regulation of Endopeptidase Activity, Inflammasome
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