Caspase 1 抗体 (Large Subunit, N-Term)
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Quick Overview for Caspase 1 抗体 (Large Subunit, N-Term) (ABIN3028535)
抗原
See all Caspase 1 (CASP1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Large Subunit, N-Term
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纯化方法
- Antigen affinity
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免疫原
- An amino acid sequence from the N-terminus of human CASP1 (CSLEEAQRIWKQKSAEIY) was used as the immunogen for this Caspase-1 antibody. The sequence is from the large subunit.
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亚型
- IgG
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应用备注
- Titration of the Caspase-1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
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限制
- 仅限研究用
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- -20 °C
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储存方法
- The lyophilized Caspase-1 antibody can be stored at 4°C. After reconstitution, aliquot and store at -20°C. Repeated freeze/thaw steps should be avoided.
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- Caspase 1 (CASP1)
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别名
- Caspase-1
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背景
- Caspase-1 is a cysteine protease that regulates inflammatory processes through its capacity to process and activate the interleukin-1-beta, interleukin 18, and interleukin 33 precursor proteins. The Caspase-1 gene consists of 10 exons spanning at least 10.6 kb and is mapped to 11q23, a site frequently involved in rearrangement in human cancers, including a number of leukemias and lymphomas.
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UniProt
- P29466
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途径
- Apoptosis, Interferon-gamma Pathway, Positive Regulation of Endopeptidase Activity, Inflammasome
抗原
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