IRAK4 抗体
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北京 101111
Quick Overview for IRAK4 抗体 (ABIN302830)
抗原
See all IRAK4 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody reacts to a synthetic peptide corresponding to amino acids at the carboxy terminus of IRAK-4.
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纯化方法
- Immunoaffinity Chromatography
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免疫原
- Synthetic peptide
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anti-Interleukin-1 Receptor-Associated Kinase 4 (IRAK4) antibody
IRAK4 适用: 人, 小鼠, 猴 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 2H9 unconjugated
anti-Interleukin-1 Receptor-Associated Kinase 4 (IRAK4) (AA 189-427) antibodyIRAK4 适用: 人 WB, ELISA, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin-1 Receptor-Associated Kinase 4 (IRAK4) (AA 1-220) antibodyIRAK4 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Interleukin-1 Receptor-Associated Kinase 4 (IRAK4) (AA 5-36), (N-Term) antibodyIRAK4 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB2347 unconjugated
anti-Interleukin-1 Receptor-Associated Kinase 4 (IRAK4) (AA 1-130) antibodyIRAK4 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2D3 unconjugated
anti-Interleukin-1 Receptor-Associated Kinase 4 (IRAK4) (N-Term) antibodyVerified IRAK4 适用: 人 WB, ELISA, IHC, FACS, IF 宿主: 山羊 Polyclonal unconjugated
anti-Interleukin-1 Receptor-Associated Kinase 4 (IRAK4) (pThr345) antibodyIRAK4 适用: 人, 小鼠, 大鼠, Cow, Pig, 犬 WB, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin-1 Receptor-Associated Kinase 4 (IRAK4) (AA 1-130) antibodyIRAK4 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1D4 unconjugated
anti-Interleukin-1 Receptor-Associated Kinase 4 (IRAK4) (AA 25-52), (N-Term) antibodyIRAK4 适用: 人 WB 宿主: 兔 Polyclonal RB33094 unconjugated
anti-Interleukin-1 Receptor-Associated Kinase 4 (IRAK4) (pThr345) antibodyIRAK4 适用: 人, 小鼠 WB, ELISA, IF (p), IHC (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western Blot: 1 - 2 μg/mL. Immunohistochemistry: 5 μg/mL. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- Phosphate buffered saline, containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C to -70 °C for longer.
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- IRAK4 (Interleukin-1 Receptor-Associated Kinase 4 (IRAK4))
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别名
- IRAK4
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背景
- IRAK4, an IRAK type protein kinase, is a signal transducer for the immune response Toll-like receptor and interleukin-1 (IL-1) receptor signaling cascades. IRAK4 has auto- and cross-phosphorylation kinase activity and has been shown to phosphorylate and activate IRAK1. Additionally, IRAK4 interacts with IRAK1 and TRAF6 in an IL-1-dependent manner, and overexpression of IRAK4 can activate NF-kappaB as well as mitogen-activated protein (MAP) kinase pathways. IRAK4 (-/-) mice are resistant to a lethal dose of lipopolysaccharide and are severely impaired in their responses to viral and bacterial challenges. At least two mRNA transcripts have been reported: 3.0- and 4.4-kb. IRAK4, also referrred to as NY-REN-64, was first identified as an anitgen in a screen of renal tumors.Synonyms: IRAK-4, Interleukin-1 receptor-associated kinase-like, NY-REN-64
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基因ID
- 51135
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NCBI登录号
- NP_001107654
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UniProt
- Q9NWZ3
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途径
- NF-kappaB Signaling, TLR signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
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