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HUWE1 抗体 (C-Term)

HUWE1 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN302816
发货至: 中国
  • 抗原 See all HUWE1 抗体
    HUWE1 (HECT, UBA and WWE Domain Containing 1, E3 Ubiquitin Protein Ligase (HUWE1))
    抗原表位
    • 15
    • 6
    • 5
    • 1
    • 1
    • 1
    C-Term
    适用
    人, 小鼠, 大鼠
    宿主
    • 33
    • 2
    • 1
    克隆类型
    • 34
    • 2
    多克隆
    标记
    • 15
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HUWE1 antibody is un-conjugated
    应用范围
    • 13
    • 13
    • 11
    • 8
    • 6
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    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
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    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody is specific to HUWE1/ARFBP1.
    纯化方法
    Immunoaffinity Chromatography.
    免疫原
    Synthetic peptide corresponding to a 19 amino acid peptide from near the carboxy terminus of ARF-BP1.
    亚型
    IgG
    Top Product
    Discover our top product HUWE1 Primary Antibody
  • 应用备注
    Western Blot: 2 μg/mL. Immunohistochemistry on Paraffin Sections: 20 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 0.09 % Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
  • 抗原
    HUWE1 (HECT, UBA and WWE Domain Containing 1, E3 Ubiquitin Protein Ligase (HUWE1))
    别名
    HUWE1 / UREB1 (HUWE1 产品)
    别名
    ARF-BP1 antibody, HECTH9 antibody, HSPC272 antibody, Ib772 antibody, LASU1 antibody, MULE antibody, URE-B1 antibody, UREB1 antibody, 5430439H10Rik antibody, AU041296 antibody, Arf-bp1 antibody, C430014N20Rik antibody, C80292 antibody, Gm1718 antibody, Mule antibody, Ureb1 antibody, HUWE1 antibody, si:dkey-242a8.2 antibody, Huwe1 antibody, mule antibody, ib772 antibody, lasu1 antibody, ureb1 antibody, hecth9 antibody, arf-bp1 antibody, hspc272 antibody, HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase antibody, HECT, UBA and WWE domain containing 1 antibody, E3 ubiquitin-protein ligase HUWE1 antibody, HUWE1 antibody, Huwe1 antibody, huwe1 antibody, LOC100123214 antibody, LOC100380641 antibody
    背景
    ARFBP1 is a novel E3 ubiquitin-protein ligase which mediates ubiquitination and subsequent proteasomal degradation of target proteins. Regulates apoptosis by catalyzing the polyubiquitination and degradation of MCL1. Also ubiquitinates the p53 tumor suppressor and core histones including H1, H2A, H2B, H3 and H4. Binds to an upstream initiator-like sequence in the preprodynorphin gene. Regulates neural differentiation and proliferation by catalyzing the polyubiquitination and degradation of MYCN. May regulate abundance of CDC6 after DNA damage by polyubiquitinating and targeting CDC6 to degradation.Synonyms: ARF-BP1, ARF-binding protein 1, E3 ubiquitin-protein ligase HUWE1, HECT, HSPC272, HectH9, Homologous to E6AP carboxyl terminus homologous protein 9, KIAA0312, KIAA1578, LASU1, Large structure of UREB1, Mcl-1 ubiquitin ligase E3, Mule, UBA and WWE domain-containing protein 1, URE-B1, URE-binding protein 1, Upstream regulatory element-binding protein 1
    基因ID
    10075
    NCBI登录号
    NP_113584
    UniProt
    Q7Z6Z7
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