CRLF2 抗体 (Center)
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- 抗原 See all CRLF2 抗体
- CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))
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抗原表位
- Center
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CRLF2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- 特异性
- This antibody detects Cytokine Receptor-like Factor 2 (CRLF2) near the center.
- 纯化方法
- Immunoaffinity Chromatography
- 免疫原
- Synthetic peptide - KLH conjugated corresponding to a 19 amino acid peptide from near the center of Human CRLF2.
- Top Product
- Discover our top product CRLF2 Primary Antibody
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anti-Cytokine Receptor-Like Factor 2 (CRLF2) (AA 81-180) antibody
CRLF2 适用: 人 ELISA, IF (p), IF (cc), IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Cytokine Receptor-Like Factor 2 (CRLF2) (AA 23-231) antibodyCRLF2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cytokine Receptor-Like Factor 2 (CRLF2) (AA 23-132) antibodyCRLF2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4A11 unconjugated
anti-Cytokine Receptor-Like Factor 2 (CRLF2) (AA 71-120) antibodyCRLF2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Cytokine Receptor-Like Factor 2 (CRLF2) (AA 23-231) antibodyCRLF2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Cytokine Receptor-Like Factor 2 (CRLF2) antibody (Carboxyfluorescein (CFS))CRLF2 适用: 小鼠 FACS 宿主: 山羊 Polyclonal Carboxyfluorescein (CFS)
anti-Cytokine Receptor-Like Factor 2 (CRLF2) (Center) antibodyCRLF2 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Cytokine Receptor-Like Factor 2 (CRLF2) antibodyCRLF2 适用: 人 WB, IHC (p), EIA 宿主: 小鼠 Monoclonal 8H8 unconjugated
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- 应用备注
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ELISA. Western blot: 1 μg/mL. Immunohistochemistry on Paraffin Sections: 5 μg/mL. Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1xTBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- PBS containing 0.02 % Sodium Azide as preservative
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- 抗原
- CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))
- 别名
- CRLF2 (CRLF2 产品)
- 别名
- CRLF2 antibody, CRL2 antibody, CRLF2Y antibody, TSLPR antibody, CRLM2 antibody, Ly114 antibody, Tpte2 antibody, Tslpr antibody, Crl2 antibody, cytokine receptor like factor 2 antibody, cytokine receptor-like factor 2 antibody, CRLF2 antibody, Crlf2 antibody
- 背景
- CRFL2 is a type I membrane receptor that forms a functional heterodimeric complex with IL7R to bind TSLP. The TSLP R contains a WSXWS motif required for proper protein folding and a box1 motif important for association with the JAKs. TSLPR has a predicted molecular weight approximately 41 kD, and two further isoforms have been reported that are produced by alternative splicing. The TSLPR is expressed preferentially in myeloid cells including dendritic cells and activated monocytes, and is weakly expressed in T cells. Expression has also been reported in heart, skeletal muscle, and kidney tissues. TSLP binding to the heterodimeric functional receptor (TSLPR and IL7R) activates JAK2, STAT3 and STAT5 to stimulate cell proliferation. Ligand receptor interactions haves been implicated in the development of the hematopoietic system, dendritic cell maturation, and the maintenance and polarization of human Th2 memory T cells in allergic diseases.Synonyms: Cytokine receptor-like 2, Cytokine receptor-like factor 2, IL-XR, ILXR, TSLPR, Thymic stromal lymphopoietin protein receptor
- 基因ID
- 64109
- NCBI登录号
- NP_071431
- UniProt
- Q9HC73
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