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Connexin 43/GJA1 抗体 (C-Term)

The 兔 多克隆 anti-Connexin 43/GJA1 antibody is suitable to detect Connexin 43/GJA1 in samples from 人. It has been validated for IHC (p).
产品编号 ABIN302618
发货至: 中国
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Quick Overview for Connexin 43/GJA1 抗体 (C-Term) (ABIN302618)

抗原

See all Connexin 43/GJA1 (GJA1) 抗体
Connexin 43/GJA1 (GJA1) (Gap Junction Protein, alpha 1, 43kDa (GJA1))

适用

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宿主

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克隆类型

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多克隆

标记

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This Connexin 43/GJA1 antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    C-Term

    特异性

    This antibody detects Connexin43 at C-terminal domain.

    纯化方法

    Immunoaffinity chromatography

    免疫原

    GJA1 antibody was raised against synthetic peptide from C-terminal domain of human GJA1 / Connexin 43.
  • 应用备注

    Immunohistochemistry on paraffin sections (10 - 20 μg/mL). Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1xTBS with Tween (TBST) for 1 min. at room temperature.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS containing 0.09 % sodium azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C for longer.
  • 抗原

    Connexin 43/GJA1 (GJA1) (Gap Junction Protein, alpha 1, 43kDa (GJA1))

    别名

    GJA1 / Cx43

    背景

    Gap junction protein, alpha 1 is a member of the connexin gene family and a component of gap junctions. Gap junctions are composed of arrays of intercellular channels and provide a route for the diffusion of materials of low molecular weight from cell to cell. Connexin 43 is the major protein of gap junctions in the heart, and gap junctions are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. Connexin 43 is targeted by several protein kinases that regulate myocardial cell-cell coupling. A related intron-less connexin 43 pseudogene, GJA1P, has been mapped to chromosome 5.Synonyms: Connexin-43, GJAL, Gap junction 43 kDa heart protein, Gap junction alpha-1 protein

    基因ID

    2697

    NCBI登录号

    NP_000156

    UniProt

    P17302

    途径

    MAPK Pathway, Myometrial Relaxation and Contraction, Cell-Cell Junction Organization
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