PODXL 抗体 (Extracellular, Intracellular, Transmembrane Domain)
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Quick Overview for PODXL 抗体 (Extracellular, Intracellular, Transmembrane Domain) (ABIN3025406)
抗原
See all PODXL 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- Extracellular, Intracellular, Transmembrane Domain
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原理
- Podocalyxin Antibody (azide and preservative free)
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纯化方法
- Protein G affinity chromatography
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免疫原
- A human recombinant protein fragment containing the intracellular, transmembrane, and part of the extracellular domain was used as the immunogen for the Podocalyxin antibody.
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亚型
- IgG1, kappa
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应用备注
- The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the Podocalyxin antibody to be titered up or down for optimal performance.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the Podocalyxin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- PODXL (Podocalyxin-Like (PODXL))
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别名
- Podocalyxin
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背景
- Podocalyxin is a member of the CD34 transmembrane sialomucin family. It is over-expressed on the podocyte foot projections and plays essential roles in kidney development and homeostasis, blood filtration and urine formation. It is also expressed on vascular endothelia, hematopoietic progenitors and a subset of neurons. Overexpression may be linked to more aggressive tumor behavior. Podocalyxin antibody can identify podocytes in the urine (podocyturia) that may indicate glomerular disease, pre-eclampsia, and other kidney pathology.
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途径
- Tube Formation
抗原
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