PODXL 抗体
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- 抗原 See all PODXL 抗体
- PODXL (Podocalyxin-Like (PODXL))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This PODXL antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunoprecipitation (IP), Immunofluorescence (IF)
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Protein G purified
- 免疫原
- Recombinant Human PODXL protein
- 克隆位点
- 4D2G7
- 亚型
- IgG2b
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anti-Podocalyxin-Like (PODXL) (Extracellular Domain) antibody
PODXL 适用: 人, 大鼠, 兔 WB, IHC, FACS, IP, IF, StM 宿主: 小鼠 Monoclonal 3D3 unconjugated
anti-Podocalyxin-Like (PODXL) (AA 32-458) antibodyPODXL 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Podocalyxin-Like (PODXL) antibodyPODXL 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 5F5 unconjugated
anti-Podocalyxin-Like (PODXL) (AA 220-431) antibodyPODXL 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Podocalyxin-Like (PODXL) (AA 171-404) antibodyPODXL 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Podocalyxin-Like (PODXL) (AA 310-447) antibodyPODXL 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal PODXL-2185 unconjugated
anti-Podocalyxin-Like (PODXL) (AA 451-558) antibodyPODXL 适用: 人, 大鼠, 小鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Podocalyxin-Like (PODXL) (AA 153-386) antibodyPODXL 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Podocalyxin-Like (PODXL) (AA 408-485) antibodyPODXL 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Podocalyxin-Like (PODXL) (Extracellular Domain) antibodyPODXL 适用: 人, 大鼠, 兔 WB, IHC, FACS, IF, StM 宿主: 小鼠 Monoclonal 2A4 unconjugated
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- 应用备注
- Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:500, IF:1:50-1:200, IP:1:200-1:2000,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- PODXL (Podocalyxin-Like (PODXL))
- 别名
- PODXL (PODXL 产品)
- 别名
- Gp200 antibody, PC antibody, PCLP antibody, PCLP-1 antibody, PCB antibody, AW121214 antibody, Ly102 antibody, Pclp1 antibody, podocalyxin antibody, MEP21 antibody, PODXL antibody, Gp135 antibody, PCLP1 antibody, cPCLP1 antibody, podxl antibody, fc18d02 antibody, wu:fc18d02 antibody, Pc antibody, Pcb antibody, Podxl antibody, podocalyxin like antibody, pyruvate carboxylase antibody, podocalyxin-like antibody, PODXL antibody, PC antibody, Podxl antibody, podxl antibody, Pcx antibody
- 背景
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Background: Involved in the regulation of both adhesion and cell morphology and cancer progression. Function as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Acts as a pro-adhesive molecule, enhancing the adherence of cells to immobilized ligands, increasing the rate of migration and cell-cell contacts in an integrin-dependent manner. Induces the formation of apical actin-dependent microvilli. Involved in the formation of a preapical plasma membrane subdomain to set up initial epithelial polarization and the apical lumen formation during renal tubulogenesis. Plays a role in cancer development and aggressiveness by inducing cell migration and invasion through its interaction with the actin-binding protein EZR. Affects EZR-dependent signaling events, leading to increased activities of the MAPK and PI3K pathways in cancer cells.
Aliases: Podocalyxin, GCTM-2 antigen, Gp200, Podocalyxin-like protein 1, PC, PCLP-1, PODXL, PCLP, PCLP1
- UniProt
- O00592
- 途径
- Tube Formation
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