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Cadherin-16 抗体

CDH16 适用: 人, 小鼠, 大鼠 IF, IHC (p) 宿主: 小鼠 Monoclonal KSCP2 unconjugated
产品编号 ABIN3024250
发货至: 中国
  • 抗原 See all Cadherin-16 (CDH16) 抗体
    Cadherin-16 (CDH16)
    适用
    • 89
    • 40
    • 31
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    • 1
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    人, 小鼠, 大鼠
    宿主
    • 55
    • 35
    • 1
    小鼠
    克隆类型
    • 49
    • 42
    单克隆
    标记
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    This Cadherin-16 antibody is un-conjugated
    应用范围
    • 40
    • 39
    • 39
    • 36
    • 25
    • 20
    • 14
    • 7
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    Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    Protein G affinity chromatography
    免疫原
    Recombinant human protein was used as the immunogen for the Cadherin 16 antibody.
    克隆位点
    KSCP2
    亚型
    IgG1 kappa
    Top Product
    Discover our top product CDH16 Primary Antibody
  • 应用备注
    Optimal dilution of the Cadherin 16 antibody to be determined by the researcher.

    1. Staining of formalin-fixed tissues requires boiling tissue sections in 10  mM Tris with 1  mM EDTA,  pH 9.0, for 10-20 min followed by cooling at RT for 20 min.
    2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Immunofluorescence: 1-2 μg/mL,Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT (1),Prediluted format: incubate for 30 min at RT (2)

    限制
    仅限研究用
  • 浓度
    0.2 mg/mL
    缓冲液
    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store the Cadherin 16 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • 抗原
    Cadherin-16 (CDH16)
    别名
    Cadherin 16 (CDH16 产品)
    别名
    cadherin 16 antibody, CDH16 antibody, Cdh16 antibody
    背景
    Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that Ksp-cadherin is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, Ksp-Cadherin is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels. Ksp-Cadherin has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.
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