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UACA 抗体

UACA 适用: 人, 小鼠 WB, IF, FACS 宿主: 小鼠 Monoclonal AE-5 unconjugated
产品编号 ABIN3024022
发货至: 中国
  • 抗原 See all UACA 抗体
    UACA
    适用
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    人, 小鼠
    宿主
    • 28
    • 14
    小鼠
    克隆类型
    • 30
    • 12
    单克隆
    标记
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    This UACA antibody is un-conjugated
    应用范围
    • 36
    • 14
    • 13
    • 13
    • 11
    • 8
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    • 5
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    Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)
    纯化方法
    Protein G affinity chromatography
    免疫原
    Nuclei of myeloid leukemia biopsy cells were used as the immunogen for the UACA antibody.
    克隆位点
    AE-5
    亚型
    IgG1 kappa
    Top Product
    Discover our top product UACA Primary Antibody
  • 应用备注
    Optimal dilution of the UACA antibody should be determined by the researcher.\. Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence: 0.5-1 μg/mL,Western blot: 0.5-1 μg/mL
    限制
    仅限研究用
  • 浓度
    0.2 mg/mL
    缓冲液
    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store the UACA antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • 抗原
    UACA
    别名
    UACA (UACA 产品)
    别名
    NUCLING antibody, 2700059D02Rik antibody, nucling antibody, RGD1560011 antibody, uveal autoantigen with coiled-coil domains and ankyrin repeats antibody, UACA antibody, Uaca antibody
    背景
    UACA (Uveal Autoantigen with Coiled-coil domains and Ankyrin repeats) is a 1,416 amino acid nuclear membrane protein. It was originally identified as an autoantigen in patients with panuveitis, a characteristic of Vogt-Koyanagi-Harada disease, and in patients with Graves' disease. UACA was also later identified as Nucling, an mRNA differentially expressed in F9 embryonal carcinoma cells during cardiac muscle differentiation. UACA appears to function as a pro-apoptotic protein that recruits the apaf-1-pro-caspase-9 complex for the induction of apoptosis to mediate the cell-death pathway.
    途径
    Positive Regulation of Endopeptidase Activity
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