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Thyroglobulin 抗体

TG 适用: 人, 小鼠, 大鼠 IHC (p) 宿主: 小鼠 Monoclonal 2H11-6E1 or TGB04-TGB05 unconjugated
产品编号 ABIN3023946
发货至: 中国
  • 抗原 See all Thyroglobulin (TG) 抗体
    Thyroglobulin (TG)
    适用
    • 95
    • 36
    • 36
    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 55
    • 39
    • 4
    • 3
    • 1
    • 1
    小鼠
    克隆类型
    • 59
    • 41
    单克隆
    标记
    • 61
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    • 2
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    This Thyroglobulin antibody is un-conjugated
    应用范围
    • 37
    • 37
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    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    Protein G affinity chromatography
    免疫原
    Human thyroid follicular cells were used as the immunogen for this Thyroglobulin antibody.
    克隆位点
    2H11-6E1 or TGB04-TGB05
    亚型
    IgG1 kappa
    Top Product
    Discover our top product TG Primary Antibody
  • 应用备注
    The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the antibody to be titered up or down for optimal performance.

    1. Staining of formalin-fixed tissues requires boiling tissue sections in 10  mM citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes.
    2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Prediluted IHC only format : incubate for 30 min at RT (2)

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Prediluted in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide, *For IHC use only*
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store the Thyroglobulin antibody cocktail at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • 抗原
    Thyroglobulin (TG)
    别名
    Thyroglobulin (TG 产品)
    别名
    TG antibody, cb717 antibody, AITD3 antibody, TGN antibody, Tgn antibody, cog antibody, thyroglobulin antibody, TG antibody, tg antibody, LOC701526 antibody, LOC701756 antibody, LOC100434297 antibody, Tg antibody
    背景
    Thyroglobulin is a 660  kDa dimeric pre-protein with mutiple glycosylation sites, detected at ~300  kDa in western blot. It is produced by and processed within the thyroid gland to produce the hormone thyroxine and triiodothyronine. Prior to forming dimers, thyroglobulin monomers undergo conformational maturation in the endoplasmic reticulation. The vast majority of follicular carcinomas of the thyroid will give positive immunoreactivity for thyroglobulin antibody even though sometimes only focally. Poorly differentiated carcinomas of the thyroid are frequently thyroglobulin negative. Adenocarcinomas of nonthyroid origin do not react with this antibody cocktail. It is useful in identification of thyroid carcinoma of the papillary and follicular types. Presence of thyroglobulin in metastatic lesions establishes the origin of the tumor. Thyroglobulin + calcitonin antibody, can identify medullary carcinomas of the thyroid. Furthermore, thyroglobulin + TTF1 antibody can be a reliable marker to differentiate between primary thyroid and lung neoplasms.
    基因ID
    7038
    途径
    Thyroid Hormone Synthesis
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