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CYP3A4 抗体 (AA 244-503)

CYP3A4 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3023346
发货至: 中国
  • 抗原 See all CYP3A4 抗体
    CYP3A4 (Cytochrome P450, Family 3, Subfamily A, Polypeptide 4 (CYP3A4))
    抗原表位
    • 16
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 244-503
    适用
    • 89
    • 38
    • 36
    • 18
    • 16
    • 13
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    宿主
    • 79
    • 9
    • 1
    克隆类型
    • 74
    • 15
    多克隆
    标记
    • 50
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This CYP3A4 antibody is un-conjugated
    应用范围
    • 72
    • 24
    • 21
    • 20
    • 19
    • 16
    • 13
    • 9
    • 5
    • 4
    • 3
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    EVTNFLRKSV KRMKESRLED TQKHRVDFLQ LMIDSQNSKE TESHKALSDL ELVAQSIIFI FAGYETTSSV LSFIMYELAT HPDVQQKLQE EIDAVLPNKA PPTYDTVLQM EYLDMVVNET LRLFPIAMRL ERVCKKDVEI NGMFIPKGVV VMIPSYALHR DPKYWTEPEK FLPERFSKKN KDNIDPYIYT PFGSGPRNCI GMRFALMNMK LALIRVLQNF SFKPCKETQI PLKLSLGGLL QPEKPVVLKV ESRDGTVSGA
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 244-503 of human CYP3A4 (NP_059488.2).
    亚型
    IgG
    Top Product
    Discover our top product CYP3A4 Primary Antibody
  • 应用备注
    WB,1:500 - 1:1000,IHC,1:20 - 1:50
    限制
    仅限研究用
  • 缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • Wei, Dai, Zhou, He, Yao, Zhao, Guo, Yang: "Oroxylin A activates PKM1/HNF4 alpha to induce hepatoma differentiation and block cancer progression." in: Cell death & disease, Vol. 8, Issue 7, pp. e2944, (2018) (PubMed).

  • 抗原
    CYP3A4 (Cytochrome P450, Family 3, Subfamily A, Polypeptide 4 (CYP3A4))
    别名
    CYP3A4 (CYP3A4 产品)
    别名
    CP33 antibody, CP34 antibody, CYP3A antibody, CYP3A3 antibody, CYPIIIA3 antibody, CYPIIIA4 antibody, HLP antibody, NF-25 antibody, P450C3 antibody, P450PCN1 antibody, MGC108372 antibody, CYP3A80 antibody, CYP3A4 antibody, CYP3A21 antibody, CYPIIIA21 antibody, CYP3A12 antibody, cytochrome P450 family 3 subfamily A member 4 antibody, cytochrome P450 family 3 subfamily A member 43 antibody, cytochrome P450 3A4 antibody, cytochrome P450, subfamily IIIA, polypeptide 4 antibody, cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4 antibody, cytochrome P450, family 3, subfamily A, polypeptide 4 antibody, CYP3A4 antibody, CYP3A43 antibody, PTRG_01782 antibody, PTRG_06060 antibody, cyp3a4 antibody
    背景
    This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs in use today, including acetaminophen, codeine, cyclosporin A, diazepam and erythromycin. The enzyme also metabolizes some steroids and carcinogens. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Previously another CYP3A gene, CYP3A3, was thought to exist, however, it is now thought that this sequence represents a transcript variant of CYP3A4. Alternatively spliced transcript variants encoding different isoforms have been identified.,CYP3A4,CP33,CP34,CYP3A,CYP3A3,CYPIIIA3,CYPIIIA4,HLP,NF-25,P450C3,P450PCN1,Cancer,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Cytochromes,Lipid Metabolism,Cytochromes,Lipases,Drug metabolism,Cardiovascular,Lipids,CYP3A4
    分子量
    57 kDa
    基因ID
    1576
    UniProt
    P08684
    途径
    Steroid Hormone Biosynthesis
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