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eIF4EBP1 抗体 (C-Term)

This anti-eIF4EBP1 antibody is a 兔 多克隆 antibody detecting eIF4EBP1 in WB, IHC 和 IF. Suitable for 人. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN3021844
发货至: 中国

Quick Overview for eIF4EBP1 抗体 (C-Term) (ABIN3021844)

抗原

See all eIF4EBP1 (EIF4EBP1) 抗体
eIF4EBP1 (EIF4EBP1) (Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1))

适用

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宿主

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克隆类型

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多克隆

标记

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This eIF4EBP1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
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    C-Term

    序列

    TRIIYDRKFL MECRNSPVTK TPPRDLPTIP GVTSPSSDEP PMEASQSHLR NSPEDKRAGG EESQFEMDI

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    A synthetic peptide corresponding to a sequence within amino acids 50 to the C-terminus of human eIF4EBP1 (NP_004086.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:1000,IHC,1:50 - 1:200,IF,1:100 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze / thaw cycles

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • Li, Chan, Yu, Bei, Chen, Zhou, Cheng, Chen, Ziegler, Rowe, Das, Xiao: "miR-29b contributes to multiple types of muscle atrophy." in: Nature communications, Vol. 8, pp. 15201, (2018) (PubMed).

    Zhou, Liu, Xue, Zheng, Liu, Ma, Li, Liu et al.: "Combination of Endothelial-Monocyte-Activating Polypeptide-II with Temozolomide Suppress Malignant Biological Behaviors of Human Glioblastoma Stem Cells via miR-590-3p/MACC1 Inhibiting PI3K/AKT/mTOR ..." in: Frontiers in molecular neuroscience, Vol. 10, pp. 68, (2017) (PubMed).

    Guo, Hu, Chen, Li, Ye, Cheng, Zhang, He: "iTRAQ-based comparative proteomic analysis of Vero cells infected with virulent and CV777 vaccine strain-like strains of porcine epidemic diarrhea virus." in: Journal of proteomics, Vol. 130, pp. 65-75, (2016) (PubMed).

  • 抗原

    eIF4EBP1 (EIF4EBP1) (Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1))

    别名

    EIF4EBP1

    背景

    This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.,4E-BP1,4EBP1,BP-1,PHAS-I,EIF4EBP1,Epigenetics & Nuclear Signaling,Translation Control,Regulation of eIF4 and p70 S6 Kinase,Signal Transduction,PI3K-Akt Signaling Pathway,mTOR Signaling Pathway,Endocrine & Metabolism,AMPK Signaling Pathway,Insulin Receptor Signaling Pathway,Endocrine and metabolic diseases,Diabetes,Metabolic disorders,Obesity,Cardiovascular,Angiogenesis,Akt downstream targets,EIF4EBP1

    分子量

    12 kDa

    基因ID

    1978

    UniProt

    Q13541

    途径

    MAPK Pathway, PI3K-Akt Signaling, RTK signaling, AMPK Signaling, Regulation of Cell Size, BCR Signaling
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