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TARDBP 抗体 (AA 1-260)

This anti-TARDBP antibody is a 兔 多克隆 antibody detecting TARDBP in WB, IP 和 RIP. Suitable for 人.
产品编号 ABIN3021656
发货至: 中国

Quick Overview for TARDBP 抗体 (AA 1-260) (ABIN3021656)

抗原

See all TARDBP 抗体
TARDBP (TAR DNA Binding Protein (TARDBP))

适用

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宿主

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克隆类型

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多克隆

标记

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This TARDBP antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP), RNA-Binding Protein Immunoprecipitation (RIP)
  • 抗原表位

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    AA 1-260

    序列

    MSEYIRVTED ENDEPIEIPS EDDGTVLLST VTAQFPGACG LRYRNPVSQC MRGVRLVEGI LHAPDAGWGN LVYVVNYPKD NKRKMDETDA SSAVKVKRAV QKTSDLIVLG LPWKTTEQDL KEYFSTFGEV LMVQVKKDLK TGHSKGFGFV RFTEYETQVK VMSQRHMIDG RWCDCKLPNS KQSQDEPLRS RKVFVGRCTE DMTEDELREF FSQYGDVMDV FIPKPFRAFA FVTFADDQIA QSLCGEDLII KGISVHISNA

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human TDP-43/TARDB (NP_031401.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IP,1:50 - 1:100,RIP,1:20 - 1:50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze / thaw cycles

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    TARDBP (TAR DNA Binding Protein (TARDBP))

    别名

    TARDBP

    背景

    HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20.,ALS10,TDP-43,TARDBP,TDP43,Epigenetics & Nuclear Signaling,RNA Binding,Cell Biology & Developmental Biology,Apoptosis,Neuroscience,Neurodegenerative Diseases,Neurodegenerative Diseases Markers,Other Neurological disorders,Amyotrophic lateral sclerosis-ALS,TARDBP

    分子量

    31 kDa/44 kDa

    基因ID

    23435

    UniProt

    Q13148

    途径

    Positive Regulation of Peptide Hormone Secretion
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