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SOX2 抗体 (AA 1-140)

SOX2 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3021003
发货至: 中国
  • 抗原 See all SOX2 抗体
    SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))
    抗原表位
    • 18
    • 16
    • 16
    • 16
    • 16
    • 15
    • 13
    • 12
    • 10
    • 10
    • 9
    • 8
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-140
    适用
    • 203
    • 96
    • 69
    • 21
    • 13
    • 11
    • 11
    • 10
    • 8
    • 8
    • 7
    • 7
    • 7
    • 5
    • 3
    • 2
    • 1
    • 1
    宿主
    • 165
    • 42
    • 2
    克隆类型
    • 162
    • 47
    多克隆
    标记
    • 103
    • 16
    • 15
    • 10
    • 10
    • 9
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SOX2 antibody is un-conjugated
    应用范围
    • 165
    • 109
    • 47
    • 45
    • 44
    • 40
    • 40
    • 28
    • 26
    • 26
    • 17
    • 15
    • 12
    • 6
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
    序列
    MYNMMETELK PPGPQQTSGG GGGNSTAAAA GGNQKNSPDR VKRPMNAFMV WSRGQRRKMA QENPKMHNSE ISKRLGAEWK LLSETEKRPF IDEAKRLRAL HMKEHPDYKY RPRRKTKTLM KKDKYTLPGG LLAPGGNSMA
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human SOX2 (NP_003097.1).
    亚型
    IgG
    Top Product
    Discover our top product SOX2 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:50 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid freeze / thaw cycles
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • Yuan, Liu, Yu, Yin, Peng, Gao, Zhu, Cao, Yang, Fan, Li: "FOXM1 contributes to taxane resistance by regulating UHRF1-controlled cancer cell stemness." in: Cell death & disease, Vol. 9, Issue 5, pp. 562, (2018) (PubMed).

    Hu, Xia, Wu, Li, Qi, Hu, Wei, Li, Tian, Wei, Shen, Yin, Jiang, Yuan, Qiang, Han, Peng: "NSPc1 promotes cancer stem cell self-renewal by repressing the synthesis of all-trans retinoic acid via targeting RDH16 in malignant glioma." in: Oncogene, Vol. 36, Issue 33, pp. 4706-4718, (2017) (PubMed).

  • 抗原
    SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))
    别名
    SOX2 (SOX2 产品)
    别名
    ANOP3 antibody, MCOPS3 antibody, RGD1565646 antibody, Sox-2 antibody, lcc antibody, ysb antibody, cb236 antibody, wu:fb83g04 antibody, wu:fc14d07 antibody, zgc:65860 antibody, zgc:77389 antibody, SRY-box2 antibody, Xsox-2 antibody, anop3 antibody, mcops3 antibody, sox-2 antibody, SRY-box 2 antibody, SRY box 2 antibody, SRY (sex determining region Y)-box 2 antibody, SRY-box 2 S homeolog antibody, SOX2 antibody, Sox2 antibody, sox2 antibody, sox2.S antibody
    背景
    This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT).,ANOP3,MCOPS3,SOX2,SRY-box 2,Epigenetics & Nuclear Signaling,Transcription Factors,Signal Transduction,Cell Biology & Developmental Biology,ESC Pluripotency and Differentiation,Neuroscience,Cell Type Marker,Stem Cells,Embryonic Stem Cells,Germline Stem Cells,Neural Stem Cell marker,SOX2
    分子量
    34 kDa
    基因ID
    6657
    UniProt
    P48431
    途径
    Dopaminergic Neurogenesis, Sensory Perception of Sound, Stem Cell Maintenance, Cell RedoxHomeostasis
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