电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

JNK 抗体 (AA 245-345)

This anti-JNK antibody is a 兔 多克隆 antibody detecting JNK in WB, IHC 和 IF. Suitable for 人. This Primary Antibody has been cited in 4+ publications.
产品编号 ABIN3020887
发货至: 中国

Quick Overview for JNK 抗体 (AA 245-345) (ABIN3020887)

抗原

See all JNK (MAPK8) 抗体
JNK (MAPK8) (Mitogen-Activated Protein Kinase 8 (MAPK8))

适用

  • 202
  • 114
  • 99
  • 40
  • 34
  • 20
  • 19
  • 9
  • 5
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1

宿主

  • 190
  • 21
  • 3
  • 1

克隆类型

  • 176
  • 39
多克隆

标记

  • 112
  • 15
  • 12
  • 9
  • 9
  • 6
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
This JNK antibody is un-conjugated

应用范围

  • 165
  • 82
  • 54
  • 48
  • 40
  • 39
  • 39
  • 26
  • 26
  • 20
  • 18
  • 12
  • 10
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

    • 52
    • 28
    • 19
    • 16
    • 16
    • 11
    • 10
    • 10
    • 8
    • 8
    • 7
    • 6
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 245-345

    序列

    CPEFMKKLQP TVRTYVENRP KYAGYSFEKL FPDVLFPADS EHNKLKASQA RDLLSKMLVI DASKRISVDE ALQHPYINVW YDPSEAEAPP PKIPDKQLDE R

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 245-345 of human JNK1 (NP_620635.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:100 - 1:200,IF,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze / thaw cycles

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • He, Zhao, Anees, Li, Ashraf, Chen, Song, Chen, Cao, Ye: "p21-Activated Kinase 4 Signaling Promotes Japanese Encephalitis Virus-Mediated Inflammation in Astrocytes." in: Frontiers in cellular and infection microbiology, Vol. 7, pp. 271, (2018) (PubMed).

    Li, Yu, Wang, Xu, Chi, Qin, Liu: "The ω-carboxyl group of 7-ketocholesteryl-9-carboxynonanoate mediates the binding of oxLDL to CD36 receptor and enhances caveolin-1 expression in macrophages." in: The international journal of biochemistry & cell biology, Vol. 90, pp. 121-135, (2017) (PubMed).

    Ma, Li, Yin, Liu, Gao, Lin, Huang, Huang, Li: "Novel role of TRPV2 in promoting the cytotoxicity of H2O2-mediated oxidative stress in human hepatoma cells." in: Free radical biology & medicine, Vol. 89, pp. 1003-13, (2016) (PubMed).

    Zhong, Wang, Liu, Li, Huang, Zhou, Lin, Lin, Yang: "Ganoderma lucidum polysaccharide peptide prevents renal ischemia reperfusion injury via counteracting oxidative stress." in: Scientific reports, Vol. 5, pp. 16910, (2016) (PubMed).

  • 抗原

    JNK (MAPK8) (Mitogen-Activated Protein Kinase 8 (MAPK8))

    别名

    MAPK8

    背景

    The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported.,MAPK8,JNK,JNK-46,JNK1,JNK1A2,JNK21B1/2,PRKM8,SAPK1,SAPK1c,Cancer,Signal Transduction,Kinase,Serine/threonine kinases,ErbB-HER Signaling Pathway,MAPK-JNK Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Mitochondrial Control of Apoptosis,Inhibition of Apoptosis,Death Receptor Signaling Pathway,TGF-b-Smad Signaling Pathway,Endocrine & Metabolism,Insulin Receptor Signaling Pathway,Immunology & Inflammation,B Cell Receptor Signaling Pathway,T Cell Receptor Signaling Pathway,NF-kB Signaling Pathway,Toll-like Receptor Signaling Pathway,Cell Intrinsic Innate Immunity Signaling Pathway,TLR Signaling,Neuroscience,Neurodegenerative Diseases,Dopamine Signaling in Parkinson's Disease,MAPK8

    分子量

    35 kDa/44 kDa/48 kDa

    基因ID

    5599

    UniProt

    P45983

    途径

    MAPK Pathway, WNT signaling, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor, S100 Proteins
You are here:
Chat with us!