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IGF1R 抗体 (AA 660-760)

This anti-IGF1R antibody is a 兔 多克隆 antibody detecting IGF1R in WB. Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN3020768
发货至: 中国

Quick Overview for IGF1R 抗体 (AA 660-760) (ABIN3020768)

抗原

See all IGF1R 抗体
IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))

适用

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宿主

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克隆类型

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多克隆

标记

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This IGF1R antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 660-760

    序列

    HNYCSKDKIP IRKYADGTID IEEVTENPKT EVCGGEKGPC CACPKTEAEK QAEKEEAEYR KVFENFLHNS IFVPRPERKR RDVMQVANTT MSSRSRNTTA A

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    A synthetic peptide corresponding to a sequence within amino acids 660-760 of human IGF1R (NP_000866.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze / thaw cycles

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • Duan, Zohaib, Li, Zhu, Ye, Wan, Xu, Song, Chen, Cao: "miR-206 modulates lipopolysaccharide-mediated inflammatory cytokine production in human astrocytes." in: Cellular signalling, Vol. 27, Issue 1, pp. 61-8, (2015) (PubMed).

    Huang, Dong, Sui, Hu, Xiong, Liao, Zhang: "MiR-223 suppresses endometrial carcinoma cells proliferation by targeting IGF-1R." in: American journal of translational research, Vol. 6, Issue 6, pp. 841-9, (2015) (PubMed).

  • 抗原

    IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))

    别名

    IGF1R

    背景

    This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.,IGF1R,CD221,IGFIR,IGFR,JTK13,Cancer,Signal Transduction,Kinase,Tyrosine kinases,Cell Biology & Developmental Biology,Apoptosis,Growth factor,Insulin and insulin-like,ESC Pluripotency and Differentiation,Immunology & Inflammation,CD markers,Cardiovascular,Angiogenesis,IGF1R

    分子量

    154 kDa

    基因ID

    3480

    UniProt

    P08069

    途径

    RTK signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Autophagy
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