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ERK1 抗体 (AA 1-100)

This anti-ERK1 antibody is a 兔 多克隆 antibody detecting ERK1 in WB, IHC 和 IF. Suitable for 人. This Primary Antibody has been cited in 8+ publications.
产品编号 ABIN3020725
发货至: 中国

Quick Overview for ERK1 抗体 (AA 1-100) (ABIN3020725)

抗原

See all ERK1 (MAPK3) 抗体
ERK1 (MAPK3) (Mitogen-Activated Protein Kinase 3 (MAPK3))

适用

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宿主

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克隆类型

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多克隆

标记

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This ERK1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
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    AA 1-100

    序列

    MAAAAAQGGG GGEPRRTEGV GPGVPGEVEM VKGQPFDVGP RYTQLQYIGE GAYGMVSSAY DHVRKTRVAI KKISPFEHQT YCQRTLREIQ ILLRFRHENV

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ERK1 (NP_002737.2).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze / thaw cycles

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • He, Zhao, Anees, Li, Ashraf, Chen, Song, Chen, Cao, Ye: "p21-Activated Kinase 4 Signaling Promotes Japanese Encephalitis Virus-Mediated Inflammation in Astrocytes." in: Frontiers in cellular and infection microbiology, Vol. 7, pp. 271, (2018) (PubMed).

    Zhu, Ye, Ashraf, Li, Chen, Song, Cao: "Transcriptional regulation of miR-15b by c-Rel and CREB in Japanese encephalitis virus infection." in: Scientific reports, Vol. 6, pp. 22581, (2017) (PubMed).

    Li, Fan, Gao, Fan, Liu: "Effect of Fructus Ligustri Lucidi on osteoblastic like cell-line MC3T3-E1." in: Journal of ethnopharmacology, Vol. 170, pp. 88-95, (2016) (PubMed).

    Wu, Qin, Guo, Li, Chen: "AKT/ERK activation is associated with gastric cancer cell resistance to paclitaxel." in: International journal of clinical and experimental pathology, Vol. 7, Issue 4, pp. 1449-58, (2015) (PubMed).

    Fan, Zhang, Hu, Li, Zhang: "Activation of AKT/ERK confers non-small cell lung cancer cells resistance to vinorelbine." in: International journal of clinical and experimental pathology, Vol. 7, Issue 1, pp. 134-43, (2014) (PubMed).

    Feng, Yu, Liu, Zhang, Cheng, Li, Tan, Luo, Jiang: "KAT5 silencing induces apoptosis of GBC-SD cells through p38MAPK-mediated upregulation of cleaved Casp9." in: International journal of clinical and experimental pathology, Vol. 7, Issue 1, pp. 80-91, (2014) (PubMed).

    Li, Wang, Pan, Wang, Fan, Sun: "RNAi screening with shRNAs against histone methylation-related genes reveals determinants of sorafenib sensitivity in hepatocellular carcinoma cells." in: International journal of clinical and experimental pathology, Vol. 7, Issue 3, pp. 1085-92, (2014) (PubMed).

    Xu, Hang, Hu, Gao: "RAF1-MEK1-ERK/AKT axis may confer NSCLC cell lines resistance to erlotinib." in: International journal of clinical and experimental pathology, Vol. 6, Issue 8, pp. 1493-504, (2013) (PubMed).

  • 抗原

    ERK1 (MAPK3) (Mitogen-Activated Protein Kinase 3 (MAPK3))

    别名

    MAPK3

    背景

    The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described.,ERK-1,ERK1,ERT2,HS44KDAP,HUMKER1A,P44ERK1,P44MAPK,PRKM3,p44-ERK1,p44-MAPK,MAPK3,Epigenetics & Nuclear Signaling,Translation Control,Regulation of eIF4 and p70 S6 Kinase,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,Kinase,Serine/threonine kinases,mTOR Signaling Pathway,ErbB-HER Signaling Pathway,MAPK-Erk Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Mitochondrial Control of Apoptosis,Inhibition of Apoptosis,Cell Cycle,Centromere,Microtubules,TGF-b-Smad Signaling Pathway,ESC Pluripotency and Differentiation,Endocrine & Metabolism,Insulin Receptor Signaling Pathway,Warburg Effect,Immunology & Inflammation,B Cell Receptor Signaling Pathway,T Cell Receptor Signaling Pathway,IL-6 Receptor Signaling Pathway,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,Stem Cells,Cardiovascular,Angiogenesis,MAPK3

    分子量

    38 kDa/40 kDa/43 kDa

    基因ID

    5595

    UniProt

    P27361

    途径

    MAPK Pathway, RTK signaling, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Response to Growth Hormone Stimulus, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals, S100 Proteins
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