LIM Domain Kinase 1 抗体 (pThr508)
Quick Overview for LIM Domain Kinase 1 抗体 (pThr508) (ABIN3020310)
抗原
See all LIM Domain Kinase 1 (LIMK1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pThr508
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Phosphorylated Antibodies
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免疫原
- A phospho specific peptide corresponding to residues surrounding T508 of human LIMK1
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亚型
- IgG
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anti-LIM Domain Kinase 1 (LIMK1) (pThr508) antibody
LIMK1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-LIM Domain Kinase 1 (LIMK1) antibodyLIMK1 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, IF, IHC (p), FACS 宿主: 小鼠 Monoclonal 3H6 unconjugated
anti-LIM Domain Kinase 1 (LIMK1) antibodyLIMK1 适用: 人, 小鼠, 大鼠, 犬, 猴 WB, IHC, IF, IHC (p), FACS 宿主: 小鼠 Monoclonal 6B4 unconjugated
anti-LIM Domain Kinase 1 (LIMK1) (AA 451-550) antibodyLIMK1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-LIM Domain Kinase 1 (LIMK1) (AA 548-647) antibodyLIMK1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1B2 unconjugated
anti-LIM Domain Kinase 1 (LIMK1) (AA 548-647) antibodyLIMK1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1A8 unconjugated
anti-LIM Domain Kinase 1 (LIMK1) (AA 548-647) antibodyLIMK1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2E9 unconjugated
anti-LIM Domain Kinase 1 (LIMK1) (pThr508) antibodyLIMK1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-LIM Domain Kinase 1 (LIMK1) (pThr508) antibodyLIMK1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-LIM Domain Kinase 1 (LIMK1) (AA 1-647) antibodyLIMK1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:100 - 1:200
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限制
- 仅限研究用
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- LIM Domain Kinase 1 (LIMK1)
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别名
- LIMK1
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背景
- There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIM kinase-1 and LIM kinase-2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain. LIMK1 is a serine/threonine kinase that regulates actin polymerization via phosphorylation and inactivation of the actin binding factor cofilin. This protein is ubiquitously expressed during development and plays a role in many cellular processes associated with cytoskeletal structure. This protein also stimulates axon growth and may play a role in brain development. LIMK1 hemizygosity is implicated in the impaired visuospatial constructive cognition of Williams syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms.,LIMK1,LIMK,LIMK-1,Signal Transduction,Kinase,Serine/threonine kinases,Tyrosine kinases,Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,Microtubules,Actins,TGF-b-Smad Signaling Pathway,Immunology & Inflammation,Neuroscience,Cell Type Marker,Neuron marker,Growth Cone,Protein phosphorylation,LIMK1
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分子量
- 33 kDa/68 kDa/70 kDa/72 kDa
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基因ID
- 3984
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UniProt
- P53667
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途径
- Caspase Cascade in Apoptosis, Regulation of Cell Size, CXCR4-mediated Signaling Events
抗原
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