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STAT2 抗体 (pTyr690)

STAT2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3020025
发货至: 中国
  • 抗原 See all STAT2 抗体
    STAT2 (Signal Transducer and Activator of Transcription 2, 113kDa (STAT2))
    抗原表位
    • 24
    • 16
    • 9
    • 8
    • 8
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr690
    适用
    • 110
    • 43
    • 36
    • 3
    宿主
    • 115
    • 6
    • 1
    克隆类型
    • 106
    • 16
    多克隆
    标记
    • 61
    • 8
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This STAT2 antibody is un-conjugated
    应用范围
    • 94
    • 52
    • 39
    • 28
    • 27
    • 19
    • 11
    • 7
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    RKYLK
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Phosphorylated Antibodies
    免疫原
    A synthetic phosphorylated peptide around Y690 of human STAT2 (NP_005410.1).
    亚型
    IgG
    Top Product
    Discover our top product STAT2 Primary Antibody
  • 应用备注
    WB,1:500 - 1:1000
    限制
    仅限研究用
  • 缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • Zhu, Wang, Zhou, Pan, Chen, Yang, Lv, Ye, Peng, Fang, Xiao: "Porcine Deltacoronavirus nsp5 Antagonizes Type I Interferon Signaling by Cleaving STAT2." in: Journal of virology, Vol. 91, Issue 10, (2017) (PubMed).

  • 抗原
    STAT2 (Signal Transducer and Activator of Transcription 2, 113kDa (STAT2))
    别名
    STAT2 (STAT2 产品)
    背景
    The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. Multiple transcript variants encoding different isoforms have been found for this gene.,STAT2,IMD44,ISGF-3,P113,STAT113,Epigenetics & Nuclear Signaling,Transcription Factors,Signal Transduction,ErbB-HER Signaling Pathway,Immunology & Inflammation,IL-6 Receptor Signaling Pathway,Protein phosphorylation,STAT2
    分子量
    97 kDa
    基因ID
    6773
    UniProt
    P52630
    途径
    JAK/STAT Signaling, Hepatitis C, CXCR4-mediated Signaling Events
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