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CAMK2A 抗体 (pThr286)

This anti-CAMK2A antibody is a 兔 多克隆 antibody detecting CAMK2A in WB. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN1681430
发货至: 中国

Quick Overview for CAMK2A 抗体 (pThr286) (ABIN1681430)

抗原

See all CAMK2A 抗体
CAMK2A (Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A))

适用

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宿主

  • 72
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克隆类型

  • 60
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多克隆

标记

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This CAMK2A antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    pThr286

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Phosphorylated Antibodies

    纯化方法

    Affinity purification

    免疫原

    A phospho specific peptide corresponding to residues surrounding T286 of human Camk2a

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    限制

    仅限研究用
  • 缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • Royer, Herzog, Kenny, Tzvetkova, Cochrane, Marr, Paradis: "The Ras-like GTPase Rem2 is a potent inhibitor of calcium/calmodulin-dependent kinase II activity." in: The Journal of biological chemistry, Vol. 293, Issue 38, pp. 14798-14811, (2018) (PubMed).

  • 抗原

    CAMK2A (Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A))

    别名

    Camk2a

    背景

    The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene.,CAMK2A,CAMKA,Cancer,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,Kinase,Serine/threonine kinases,Phospholipase Signaling Pathway,ErbB-HER Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Mitochondrial Control of Apoptosis,Microtubules,Endocrine & Metabolism,Carbohydrate metabolism,Immunology & Inflammation,B Cell Receptor Signaling Pathway,Neuroscience,Calcium Signaling,Cardiovascular,Heart,Hypertrophy,Protein phosphorylation,Camk2a

    分子量

    22 kDa/54 kDa

    基因ID

    815

    UniProt

    Q9UQM7

    途径

    WNT signaling, Interferon-gamma Pathway, Myometrial Relaxation and Contraction
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