CAMK2A 抗体 (pThr286)
Quick Overview for CAMK2A 抗体 (pThr286) (ABIN1681430)
抗原
See all CAMK2A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pThr286
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Phosphorylated Antibodies
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纯化方法
- Affinity purification
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免疫原
- A phospho specific peptide corresponding to residues surrounding T286 of human Camk2a
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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: "The Ras-like GTPase Rem2 is a potent inhibitor of calcium/calmodulin-dependent kinase II activity." in: The Journal of biological chemistry, Vol. 293, Issue 38, pp. 14798-14811, (2018) (PubMed).
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: "The Ras-like GTPase Rem2 is a potent inhibitor of calcium/calmodulin-dependent kinase II activity." in: The Journal of biological chemistry, Vol. 293, Issue 38, pp. 14798-14811, (2018) (PubMed).
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- CAMK2A (Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A))
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别名
- Camk2a
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背景
- The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene.,CAMK2A,CAMKA,Cancer,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,Kinase,Serine/threonine kinases,Phospholipase Signaling Pathway,ErbB-HER Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Mitochondrial Control of Apoptosis,Microtubules,Endocrine & Metabolism,Carbohydrate metabolism,Immunology & Inflammation,B Cell Receptor Signaling Pathway,Neuroscience,Calcium Signaling,Cardiovascular,Heart,Hypertrophy,Protein phosphorylation,Camk2a
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分子量
- 22 kDa/54 kDa
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基因ID
- 815
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UniProt
- Q9UQM7
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途径
- WNT signaling, Interferon-gamma Pathway, Myometrial Relaxation and Contraction
抗原
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