PRKCA/PRKCB (pThr638), (pThr641) 抗体
适用: 人
IF, IHC, WB
宿主: 兔
Polyclonal
unconjugated
-
- 抗原
- PRKCA/PRKCB
- 抗原表位
- pThr638, pThr641
- 适用
- 人
- 宿主
- 兔
- 克隆类型
- 多克隆
- 应用范围
- Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
- Phosphorylated Antibodies
- 纯化方法
- Affinity purification
- 免疫原
- A phospho specific peptide corresponding to residues surrounding T638/641 of human PKCalpha/beta II
- 亚型
- IgG
-
- 应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:100 - 1:200
- 限制
- 仅限研究用
-
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
- 抗原
- PRKCA/PRKCB
- 背景
- Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. Studies in mice also suggest that this kinase may also regulate neuronal functions and correlate fear-induced conflict behavior after stress. Alternatively spliced transcript variants encoding distinct isoforms have been reported.,PKC-beta,PKCB,PRKCB1,PRKCB2,Protein phosphorylation,Protein phosphorylation,Protein phosphorylation,PRKCA/PRKCB
- 分子量
- 76 kDa/77 kDa
- 基因ID
- 5578, 5579
- UniProt
- P17252, P05771
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