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ADAMTS5 抗体 (AA 731-930)

ADAMTS5 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3016806
发货至: 中国
  • 抗原 See all ADAMTS5 抗体
    ADAMTS5 (ADAM Metallopeptidase with thrombospondin Type 1 Motif, 5 (ADAMTS5))
    抗原表位
    • 15
    • 8
    • 8
    • 7
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 731-930
    适用
    • 54
    • 27
    • 20
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 52
    • 3
    • 2
    克隆类型
    • 54
    • 3
    多克隆
    标记
    • 25
    • 5
    • 5
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ADAMTS5 antibody is un-conjugated
    应用范围
    • 47
    • 29
    • 10
    • 9
    • 7
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 731-930 of human ADAMTS5 (NP_008969.2).
    亚型
    IgG
  • 应用备注
    WB,1:500 - 1:2000,IF,1:50 - 1:200
    限制
    仅限研究用
  • 缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • Si, Zeng, Liu, Zhou, Chen, Cheng, Lu, Shen: "Intra-articular injection of microRNA-140 (miRNA-140) alleviates osteoarthritis (OA) progression by modulating extracellular matrix (ECM) homeostasis in rats." in: Osteoarthritis and cartilage, Vol. 25, Issue 10, pp. 1698-1707, (2018) (PubMed).

  • 抗原
    ADAMTS5 (ADAM Metallopeptidase with thrombospondin Type 1 Motif, 5 (ADAMTS5))
    别名
    ADAMTS5 (ADAMTS5 产品)
    别名
    9530092O11Rik antibody, ADAM-TS5 antibody, ADAMTS1 antibody, ADAMTS11 antibody, AI481094 antibody, ASMP-2 antibody, ADAM-TS 11 antibody, ADAM-TS 5 antibody, ADAMTS-11 antibody, ADAMTS-5 antibody, ADMP-2 antibody, ADAM metallopeptidase with thrombospondin type 1 motif 5 antibody, a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2) antibody, ADAM metallopeptidase with thrombospondin type 1 motif, 5 antibody, ADAMTS5 antibody, adamts5 antibody, Adamts5 antibody
    背景
    This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme contains two C-terminal TS motifs and functions as an aggrecanase that cleaves aggrecan, a major proteoglycan of cartilage, and may mediate cartilage destruction in osteoarthritis.,ADAMTS5,ADAM-TS 11,ADAM-TS 5,ADAM-TS5,ADAMTS-11,ADAMTS-5,ADAMTS11,ADMP-2,ADAM-TS11,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,ADAM Protein Family,MMPs,Ubiquitin,ADAMTS5
    分子量
    101 kDa
    基因ID
    11096
    UniProt
    Q9UNA0
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