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TNK2 抗体 (AA 70-385)

TNK2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1683072
发货至: 中国
  • 抗原 See all TNK2 抗体
    TNK2 (tyrosine Kinase, Non-Receptor, 2 (TNK2))
    抗原表位
    • 22
    • 15
    • 13
    • 9
    • 8
    • 8
    • 8
    • 8
    • 7
    • 7
    • 6
    • 6
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 70-385
    适用
    • 123
    • 51
    • 46
    • 3
    • 2
    • 2
    宿主
    • 120
    • 3
    • 1
    克隆类型
    • 122
    • 1
    多克隆
    标记
    • 50
    • 11
    • 11
    • 9
    • 8
    • 7
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    This TNK2 antibody is un-conjugated
    应用范围
    • 96
    • 69
    • 26
    • 26
    • 26
    • 20
    • 16
    • 12
    • 8
    • 6
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB)
    序列
    TGWLLELLSE VQLQQYFLRL RDDLNVTRLS HFEYVKNEDL EKIGMGRPGQ RRLWEAVKRR KALCKRKSWM SKVFSGKRLE AEFPPHHSQS TFRKTSPAPG GPAGEGPLQS LTCLIGEKDL RLLEKLGDGS FGVVRRGEWD APSGKTVSVA VKCLKPDVLS QPEAMDDFIR EVNAMHSLDH RNLIRLYGVV LTPPMKMVTE LAPLGSLLDR LRKHQGHFLL GTLSRYAVQV AEGMGYLESK RFIHRDLAAR NLLLATRDLV KIGDFGLMRA LPQNDDHYVM QEHRKVPFAW CAPESLKTRT FSHASDTWMF GVTLWE
    交叉反应
    产品特性
    Polyclonal Antibodies
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 70-385 of human TNK2 (NP_001010938.1).
    亚型
    IgG
  • 应用备注
    WB,1:500 - 1:2000
    限制
    仅限研究用
  • 缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • Hu, Xu, Yin, Zhang, Lu, Wu, Xue, Ho, Gao, Zhao, Zhang: "Ack promotes tissue growth via phosphorylation and suppression of the Hippo pathway component Expanded." in: Cell discovery, Vol. 2, pp. 15047, (2016) (PubMed).

  • 抗原
    TNK2 (tyrosine Kinase, Non-Receptor, 2 (TNK2))
    别名
    TNK2 (TNK2 产品)
    别名
    ACK antibody, ACK-1 antibody, ACK1 antibody, p21cdc42Hs antibody, AW552477 antibody, Ack antibody, Cdgip antibody, Pyk1 antibody, ack1 antibody, ackb antibody, tnk2 antibody, tnk2b antibody, wu:fj16g04 antibody, zgc:154019 antibody, tyrosine kinase non receptor 2 antibody, tyrosine kinase, non-receptor, 2 antibody, tyrosine kinase, non-receptor, 1 antibody, TNK2 antibody, Tnk2 antibody, tnk1 antibody
    背景
    This gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined.,TNK2,ACK,ACK-1,ACK1,p21cdc42Hs,Epigenetics & Nuclear Signaling,Nuclear Receptor Signaling,Cancer,Signal Transduction,G protein signaling,Signal Transduction,Kinase,Tyrosine kinases,Cell Biology & Developmental Biology,Cell Cycle,Growth factor,EGF,TNK2
    分子量
    60 kDa/114 kDa/119 kDa
    基因ID
    10188
    UniProt
    Q07912
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