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FMO3 抗体 (AA 263-532)

This anti-FMO3 antibody is a 兔 多克隆 antibody detecting FMO3 in WB 和 IF. Suitable for 人.
产品编号 ABIN3015686
发货至: 中国

Quick Overview for FMO3 抗体 (AA 263-532) (ABIN3015686)

抗原

See all FMO3 抗体
FMO3 (Flavin Containing Monooxygenase 3 (FMO3))

适用

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宿主

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克隆类型

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多克隆

标记

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This FMO3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF)
  • 抗原表位

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    AA 263-532

    序列

    RFKHENYGLM PLNGVLRKEP VFNDELPASI LCGIVSVKPN VKEFTETSAI FEDGTIFEGI DCVIFATGYS FAYPFLDESI IKSRNNEIIL FKGVFPPLLE KSTIAVIGFV QSLGAAIPTV DLQSRWAAQV IKGTCTLPSM EDMMNDINEK MEKKRKWFGK SETIQTDYIV YMDELSSFIG AKPNIPWLFL TDPKLAMEVY FGPCSPYQFR LVGPGQWPGA RNAILTQWDR SLKPMQTRVV GRLQKPCFFF HWLKLFAIPI LLIAVFLVLT

    交叉反应

    人, 小鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 263-532 of human FMO3 (NP_001002294.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IF,1:10 - 1:100

    限制

    仅限研究用
  • 缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    FMO3 (Flavin Containing Monooxygenase 3 (FMO3))

    别名

    FMO3

    背景

    Flavin-containing monooxygenases (FMO) are an important class of drug-metabolizing enzymes that catalyze the NADPH-dependent oxygenation of various nitrogen-,sulfur-, and phosphorous-containing xenobiotics such as therapeutic drugs, dietary compounds, pesticides, and other foreign compounds. The human FMO gene family is composed of 5 genes and multiple pseudogenes. FMO members have distinct developmental- and tissue-specific expression patterns. The expression of this FMO3 gene, the major FMO expressed in adult liver, can vary up to 20-fold between individuals. This inter-individual variation in FMO3 expression levels is likely to have significant effects on the rate at which xenobiotics are metabolised and, therefore, is of considerable interest to the pharmaceutical industry. This transmembrane protein localizes to the endoplasmic reticulum of many tissues. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. Mutations in this gene cause the disorder trimethylaminuria (TMAu) which is characterized by the accumulation and excretion of unmetabolized trimethylamine and a distinctive body odor. In healthy individuals, trimethylamine is primarily converted to the non odorous trimethylamine N-oxide.,FMO3,FMOII,TMAU,dJ127D3.1,Signal Transduction,Endocrine & Metabolism,Drug metabolism,FMO3

    分子量

    60 kDa

    基因ID

    2328

    UniProt

    P31513
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