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ADRB3 抗体

ADRB3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN290046
发货至: 中国
  • 抗原 See all ADRB3 抗体
    ADRB3 (Adrenergic, beta-3-, Receptor (ADRB3))
    适用
    • 55
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    宿主
    • 53
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    克隆类型
    • 59
    多克隆
    标记
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    This ADRB3 antibody is un-conjugated
    应用范围
    • 46
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    Western Blotting (WB)
    纯化方法
    This antibody was prepared from the serum of a rabbit immunized with a partial peptide representing the C-terminal domain of Human beta3-AR, and purified by peptide affinity chromatography.
    免疫原
    Partial peptide of Human beta3-AR
    Top Product
    Discover our top product ADRB3 Primary Antibody
  • 应用备注
    Working dilution For Western blotting: 5.0ug/ml
    限制
    仅限研究用
  • 浓度
    0.25 mg/ml
    缓冲液
    PBS (containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat)
    储存液
    ProClin
    储存条件
    -20 °C
  • 抗原
    ADRB3 (Adrenergic, beta-3-, Receptor (ADRB3))
    别名
    beta3-AR (ADRB3 产品)
    别名
    BETA3AR antibody, Adrb-3 antibody, ADRB antibody, BAR3 antibody, B3AR antibody, GPCR antibody, im:7154935 antibody, si:ch211-215f19.1 antibody, zgc:194843 antibody, zgc:194852 antibody, adrenoceptor beta 3 antibody, adrenergic receptor, beta 3 antibody, adrenoceptor beta 3a antibody, adrenoceptor beta 3b antibody, ADRB3 antibody, Adrb3 antibody, adrb3a antibody, adrb3b antibody
    背景
    The neurotransmitter/hormone adrenaline (epinephrine, adrenalin) plays a central role in the mammalianstress response, increasing heart rate, raising blood pressure, and increasing blood glucose levels upon enteringthe blood stream.Adrenaline is secreted primarily by the adrenal medulla. Adrenaline activates both alpha-adrenergic receptors and beta-adrenergic receptors. Three subtypes of beta adrenergic receptors are known, beta1, beta2, beta3, expressed primarily inheart, respiratory tissue, and adipose tissue, respectively. Beta3-receptors are particularly abundant in brown adipocytes and play important roles in lipolysis andtheremoregulation. (Ref.1, Ref.2) Recently this receptor has received attention from researchers intereseted in type 2diabetes mellitus and obesity. It is also being considered as a therapertic target for heart failure (Ref.3).
    途径
    cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Feeding Behaviour, Brown Fat Cell Differentiation
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