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Adiponectin Receptor 1 抗体

ADIPOR1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN290045
发货至: 中国
  • 抗原 See all Adiponectin Receptor 1 (ADIPOR1) 抗体
    Adiponectin Receptor 1 (ADIPOR1)
    适用
    • 75
    • 33
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    • 10
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    宿主
    • 71
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    克隆类型
    • 65
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    多克隆
    标记
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    This Adiponectin Receptor 1 antibody is un-conjugated
    应用范围
    • 58
    • 30
    • 18
    • 14
    • 14
    • 9
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody was prepared from the serum of a rabbit immunized with a partial peptide representing the N-terminal domain of Human AdipoR1, and purified bypeptide affinity chromatography.
    免疫原
    Partial peptide of Human AdipoR1
    Top Product
    Discover our top product ADIPOR1 Primary Antibody
  • 应用备注
    Working dilution For Western blotting: 1.0ug/ml
    限制
    仅限研究用
  • 浓度
    0.25 mg/ml
    缓冲液
    PBS (containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat)
    储存液
    ProClin
    储存条件
    -20 °C
  • 抗原
    Adiponectin Receptor 1 (ADIPOR1)
    别名
    AdipoR1 (ADIPOR1 产品)
    别名
    ADIPOR1 antibody, adipor1 antibody, zgc:92893 antibody, ACDCR1 antibody, CGI45 antibody, PAQR1 antibody, TESBP1A antibody, 2810031L11Rik antibody, CGI-45 antibody, Paqr1 antibody, zgc:55386 antibody, wu:fj02d08 antibody, acdcr1 antibody, cgi-45 antibody, cgi45 antibody, paqr1 antibody, tesbp1a antibody, MGC53458 antibody, Adipor1 antibody, adiponectin receptor 1 antibody, adiponectin receptor 1a antibody, adiponectin receptor 1b antibody, adiponectin receptor 1 S homeolog antibody, adiponectin receptor 1 L homeolog antibody, ADIPOR1 antibody, adipor1a antibody, Adipor1 antibody, adipor1b antibody, adipor1 antibody, adipor1.S antibody, adipor1.L antibody
    背景
    Obesity is a common etiology of diabetes mellitus and other diseases. Certain adipocytokines areconsidered beneficial due to their ability to enhance insulin sensitivity, while others, considereddetrimental, enhance insulin resistance.The beneficial adipocytokine adiponectin displays both anti-diabetic and anti-arteriosclerotic effects. Two distinct adiponectin receptors have been identified. Both AdipoR1 and AdipoR2 are seven-passtransmembrane receptors but are structurally, topologically, and functionally distinct from G-proteincoupled receptors (GPCR) (Ref.1). AdipoR1 is most abundant in muscle whereas AdipoR2 is mostabundant in liver. Both receptors promote fatty acid oxidation and glucose uptake by AMP-activatedprotein kinase and PPAR gamma.PPAR agonists are reported to increase expression of activated adiponectin. PPAR gamma agonists also increase expression of adiponectin receptors (Ref.2). Such findings have focused attention on the role of AdipoR1 in PPAR agonist development.
    途径
    AMPK Signaling
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