TNF alpha 抗体
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北京 101111
Quick Overview for TNF alpha 抗体 (ABIN289547)
抗原
See all TNF alpha 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Purified
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免疫原
- TNF alpha antibody was raised in goat using highly pure recombinant human TNF-alpha as the immunogen.
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亚型
- IgG1 kappa
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应用备注
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ELISA: 0.5-2 µg/mL, Inhibition: 0.012-0.014 µg/mL, WB: 0.1-0.2 µg/mL
Optimal conditions should be determined by the investigator. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Reconstitute in sterile water to a concentration of > 0.2 mg/mL.
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浓度
- Lot specific
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缓冲液
- Lyophilized from 0.5 x PBS, pH 7.4.
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.
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- TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))
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别名
- TNF alpha
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背景
- TNF-alpha is a pleiotropic pro-inflammatory cytokine secreted by various cells including adipocytes, activated monocytes, macrophages, B cells, T cells and fibroblasts. It belongs to the TNF family of ligands and signals through two receptors, TNFR1 and TNFR2. TNF-alpha is cytotoxic to a wide variety of tumor cells and is an essential factor in mediating the immune response against bacterial infections. TNF-alpha also plays a role in the induction of septic shock, auto immune diseases, rheumatoid arthritis, inflammation, and diabetes.
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分子量
- 17.3 kDa (predicted detection band MW)
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途径
- NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, TLR signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Inflammasome
抗原
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