Survivin 抗体 (AA 125-142)
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北京 101111
Quick Overview for Survivin 抗体 (AA 125-142) (ABIN289546)
抗原
See all Survivin (BIRC5) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 125-142
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特异性
- This antibody will recognize wild type Rev protein produced from both in vivo (expression in COS, CV-1, HeLa cell lines) and in vitro (E. coli bacterial expressionsystem and translation products). Very low crossreactivity with other E. coli proteinson western blot. Crossreactivity with other GST fusion proteins will occur unless preabsorbed against GST.
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交叉反应
- 小鼠, 大鼠
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交叉反应 (详细)
- This antibody reacts with residues 125-142 EETAKKVRRAIEQLAAMD of the human Survivin protein. Cross reacts with mouse and rat Survivin (88% sequenceidentity).
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纯化方法
- Affinity chromatography purified
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免疫原
- Survivin antibody was raised in rabbit using AA 125-142 EETAKKVRRAIEQLAAMD of the human survivin protein as the immunogen.
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亚型
- IgG
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应用备注
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WB: 1:500-1:1,000
Optimal conditions should be determined by the investigator. -
限制
- 仅限研究用
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浓度
- Lot specific
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缓冲液
- Supplied in PBS, with 0.02 % NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.
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- Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))
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别名
- Survivin
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背景
- Survivin is a human gene encoding a structurally unique IAP apoptosis inhibitor. Present during fetal development, survivin is undetectable in terminally differentiated adult tissues. However, survivin becomes prominently expressed in transformed cell lines and in all the most common human cancers of lung, colon, pancreas, prostate and breast, in vivo.
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途径
- Apoptosis, Cell Division Cycle, Nuclear Hormone Receptor Binding
抗原
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