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Survivin 抗体 (AA 125-142)

This 兔 多克隆 antibody specifically detects Survivin in WB. It exhibits reactivity toward 人.
产品编号 ABIN289546
发货至: 中国
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Quick Overview for Survivin 抗体 (AA 125-142) (ABIN289546)

抗原

See all Survivin (BIRC5) 抗体
Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))

适用

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宿主

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克隆类型

  • 95
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多克隆

标记

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This Survivin antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 125-142

    特异性

    This antibody will recognize wild type Rev protein produced from both in vivo (expression in COS, CV-1, HeLa cell lines) and in vitro (E. coli bacterial expressionsystem and translation products). Very low crossreactivity with other E. coli proteinson western blot. Crossreactivity with other GST fusion proteins will occur unless preabsorbed against GST.

    交叉反应

    小鼠, 大鼠

    交叉反应 (详细)

    This antibody reacts with residues 125-142 EETAKKVRRAIEQLAAMD of the human Survivin protein. Cross reacts with mouse and rat Survivin (88% sequenceidentity).

    纯化方法

    Affinity chromatography purified

    免疫原

    Survivin antibody was raised in rabbit using AA 125-142 EETAKKVRRAIEQLAAMD of the human survivin protein as the immunogen.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:1,000
    Optimal conditions should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    Lot specific

    缓冲液

    Supplied in PBS, with 0.02 % NaN3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.
  • 抗原

    Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))

    别名

    Survivin

    背景

    Survivin is a human gene encoding a structurally unique IAP apoptosis inhibitor. Present during fetal development, survivin is undetectable in terminally differentiated adult tissues. However, survivin becomes prominently expressed in transformed cell lines and in all the most common human cancers of lung, colon, pancreas, prostate and breast, in vivo.

    途径

    Apoptosis, Cell Division Cycle, Nuclear Hormone Receptor Binding
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