IL-6 抗体
Quick Overview for IL-6 抗体 (ABIN289357)
抗原
See all IL-6 (IL6) 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Purified
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免疫原
- IL6 antibody was raised in rabbit using highly pure recombinant murine IL-6 as the immunogen.
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应用备注
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ELISA: 0.5-2 µg/mL, Inhibition: 0.24-0.36 µg/mL, WB: 0.1-0.2 µg/mL
Optimal conditions should be determined by the investigator. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Reconstitute in sterile water to a concentration > 0.2 mg/mL.
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浓度
- Lot specific
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缓冲液
- Lyophilized from PBS, pH 7.4.
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.
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- IL-6 (IL6) (Interleukin 6 (IL6))
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别名
- IL6
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背景
- IL6 is a pleiotropic cytokine that plays an important role in host defense by regulating immune and inflammatory responses. Produced by T cells, monocytes, fibroblasts, endothelial cells and keratinocytes, IL6 has diverse biological functions. It stimulates B-cell differentiation and antibody production, synergizes with IL3 in megakaryocyte development and platelet production, induces expression of hepatic acute-phase proteins, and regulates bone metabolism. IL6 signals through the IL6 receptor system that consists of two chains, IL6R alpha and gp130. Mouse IL6 is inactive on human cells, while both human and Mouse are equally active on Mouse cells.
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分子量
- 21.7 kDa (predicted detection band MW)
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途径
- TLR signaling, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagy, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome
抗原
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