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IL-6 抗体

This anti-IL-6 antibody is a 兔 多克隆 antibody detecting IL-6 in WB, ELISA 和 Inhibition. Suitable for 小鼠.
产品编号 ABIN289357
发货至: 中国

Quick Overview for IL-6 抗体 (ABIN289357)

抗原

See all IL-6 (IL6) 抗体
IL-6 (IL6) (Interleukin 6 (IL6))

适用

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小鼠

宿主

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克隆类型

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多克隆

标记

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This IL-6 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Blocking Antibody (Inhibition)
  • 纯化方法

    Purified

    免疫原

    IL6 antibody was raised in rabbit using highly pure recombinant murine IL-6 as the immunogen.
  • 应用备注

    ELISA: 0.5-2 µg/mL, Inhibition: 0.24-0.36 µg/mL, WB: 0.1-0.2 µg/mL
    Optimal conditions should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Reconstitute in sterile water to a concentration > 0.2 mg/mL.

    浓度

    Lot specific

    缓冲液

    Lyophilized from PBS, pH 7.4.

    注意事项

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.
  • 抗原

    IL-6 (IL6) (Interleukin 6 (IL6))

    别名

    IL6

    背景

    IL6 is a pleiotropic cytokine that plays an important role in host defense by regulating immune and inflammatory responses. Produced by T cells, monocytes, fibroblasts, endothelial cells and keratinocytes, IL6 has diverse biological functions. It stimulates B-cell differentiation and antibody production, synergizes with IL3 in megakaryocyte development and platelet production, induces expression of hepatic acute-phase proteins, and regulates bone metabolism. IL6 signals through the IL6 receptor system that consists of two chains, IL6R alpha and gp130. Mouse IL6 is inactive on human cells, while both human and Mouse are equally active on Mouse cells.

    分子量

    21.7 kDa (predicted detection band MW)

    途径

    TLR signaling, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagy, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome
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