IL1A 抗体
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北京 101111
Quick Overview for IL1A 抗体 (ABIN289344)
抗原
See all IL1A 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Purified
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免疫原
- IL1 a antibody was raised in rabbit using highly pure recombinant murine IL-1 as the immunogen.
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应用备注
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ELISA: 0.5-2 µg/mL, Inhibition: 0.03-0.05 µg/mL, WB: 0.1-0.2 µg/mL
Optimal conditions should be determined by the investigator. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Reconstitute in sterile water at a concentration of >0.2 mg/mL.
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浓度
- Lot specific
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缓冲液
- Lyophilized from PBS, pH 7.2.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.
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- IL1A (Interleukin 1 alpha (IL1A))
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别名
- IL1a
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背景
- IL1a is a non-secreted proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL1a and IL1beta binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL2 release, B-cell maturation and proliferation, mitogenic FGFlike activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL1beta is a secreted cytokine, IL1a is predominantly a cell-associated cytokine.
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分子量
- 17.7 kDa (predicted detection band MW)
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途径
- NF-kappaB Signaling, Autophagy, Cancer Immune Checkpoints
抗原
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