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BAK1 抗体 (N-Term)

This anti-BAK1 antibody is a 兔 多克隆 antibody detecting BAK1 in WB 和 IHC (p). Suitable for 人.
产品编号 ABIN2857046
发货至: 中国

Quick Overview for BAK1 抗体 (N-Term) (ABIN2857046)

抗原

See all BAK1 抗体
BAK1 (BCL2-Antagonist/killer 1 (BAK1))

适用

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宿主

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克隆类型

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多克隆

标记

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This BAK1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    N-Term

    交叉反应

    产品特性

    Rabbit Polyclonal antibody to BAK (BCL2-antagonist/killer 1)
    BAK antibody [N1N2], N-term

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human BAK. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Validation: Orthogonal

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    BAK1 (BCL2-Antagonist/killer 1 (BAK1))

    别名

    BCL2 antagonist/killer 1

    背景

    The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.

    Cellular Localization: Membrane

    分子量

    23 kDa

    基因ID

    578

    UniProt

    Q16611

    途径

    Apoptosis, Steroid Hormone Mediated Signaling Pathway, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
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